Daptomycin and Letermovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Daptomycin (daptomycin) and Letermovir (letermovir). Common drug interactions include drug ineffective among females and drug level increased among males.

The phase IV clinical study analyzes what interactions people have when they take Daptomycin and Letermovir. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Daptomycin?

Daptomycin has active ingredients of daptomycin. eHealthMe is studying from 7,879 Daptomycin users. Check the latest studies of Daptomycin.

What is Letermovir?

Letermovir has active ingredients of letermovir. eHealthMe is studying from 949 Letermovir users. Check the latest studies of Letermovir.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 17, 2026

36 people who take Daptomycin and Letermovir together, and have interactions are studied.

Daptomycin and Letermovir drug interactions.

What are the common drug interactions of Daptomycin and Letermovir, by gender? *:

female:

  1. Drug ineffective
  2. Drug resistance (reduction in effectiveness of a drug)
  3. Hepatic haematoma (collection of blood outside of blood vessels in liver)
  4. Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
  5. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  6. Agitation (state of anxiety or nervous excitement)
  7. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  8. Blindness cortical
  9. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  10. Confusional state

male:

  1. Drug level increased
  2. Hepatic failure (liver failure)
  3. Pancreatitis acute (sudden inflammation of pancreas)
  4. Platelet count decreased
  5. Polyomavirus-associated nephropathy (polyomavirus-associated kidney disease)
  6. Renal impairment (severely reduced kidney function)
  7. White blood cell count decreased
  8. Septic shock (shock due to blood infection)
  9. Altered state of consciousness (altered state of mind)
  10. Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)

What are the common drug interactions of Daptomycin and Letermovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
  2. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  3. Biliary colic
  4. Candida sepsis (candida in blood stream)
  5. Haemoglobin decreased
  6. Pancreatitis acute (sudden inflammation of pancreas)
  7. Platelet count decreased
  8. Polyomavirus-associated nephropathy (polyomavirus-associated kidney disease)
  9. Renal impairment (severely reduced kidney function)
  10. White blood cell count decreased

20-29:

  1. Drug ineffective
  2. Drug resistance (reduction in effectiveness of a drug)
  3. Hepatic haematoma (collection of blood outside of blood vessels in liver)
  4. Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
  5. Cytomegalovirus infection
  6. Electrolyte imbalance
  7. Haemoperitoneum (presence of blood in the peritoneal cavity)
  8. Myelosuppression (a decrease in the production of blood cells)
  9. Nephropathy toxic (damage to kidney due to toxins)
  10. Neutropenia (an abnormally low number of neutrophils)

30-39:

n/a

40-49:

n/a

50-59:

  1. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  2. Confusional state
  3. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  4. Agitation (state of anxiety or nervous excitement)
  5. Blindness cortical

60+:

  1. Drug level increased
  2. Hepatic failure (liver failure)
  3. Septic shock (shock due to blood infection)
  4. Altered state of consciousness (altered state of mind)
  5. Depressed level of consciousness
  6. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  7. Leukopenia (less number of white blood cells in blood)

What are the existing conditions these people have? *

  1. Pneumonia: 3 people, 8.33%
  2. Fever: 3 people, 8.33%
  3. Cytomegalovirus Infection: 3 people, 8.33%
  4. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 8.33%
  5. Venoocclusive Disease (small veins in the liver are obstructed): 2 people, 5.56%
  6. Staphylococcal Sepsis (blood infection by an infection with staphylococcus bacteria): 2 people, 5.56%
  7. Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 5.56%
  8. Adenovirus Infection: 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Daptomycin and Letermovir?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Daptomycin and Letermovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Daptomycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Letermovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Daptomycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Letermovir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on daptomycin and letermovir (the active ingredients of Daptomycin and Letermovir, respectively), and Daptomycin and Letermovir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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