Daptomycin and Lidoderm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Daptomycin (daptomycin) and Lidoderm (lidocaine). Common drug interactions include tooth extraction among females and cytomegalovirus infection among males.

The phase IV clinical study analyzes what interactions people have when they take Daptomycin and Lidoderm. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Daptomycin?

Daptomycin has active ingredients of daptomycin. eHealthMe is studying from 7,879 Daptomycin users. Check the latest studies of Daptomycin.

What is Lidoderm?

Lidoderm has active ingredients of lidocaine. It is often used in pain. eHealthMe is studying from 10,524 Lidoderm users. Check the latest studies of Lidoderm.



On Jul, 13, 2026

20 people who take Daptomycin and Lidoderm together, and have interactions are studied.

Daptomycin and Lidoderm drug interactions.

What are the common drug interactions of Daptomycin and Lidoderm, by gender? *:

female:

  1. Tooth extraction
  2. Varicose vein (veins that have become enlarged and tortuous)
  3. Activities of daily living impaired
  4. Adrenal disorder
  5. Adrenal mass
  6. Bipolar disorder (mood disorder)
  7. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  8. Brain neoplasm (tumour of brain)
  9. Breast mass
  10. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)

male:

  1. Cytomegalovirus infection
  2. Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
  3. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  4. Death
  5. Femur fracture
  6. Hypervolaemia (abnormally increased volume of blood)
  7. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  8. Intestinal pseudo-obstruction (syndrome caused by severe impairment in the ability of the intestines to push food through)
  9. Joint effusion (presence of extra fluid in joint covering)
  10. Mucormycosis (a rare infection caused by organisms that belong to a group of fungi called mucoromycotina)

What are the common drug interactions of Daptomycin and Lidoderm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Arthralgia (joint pain)
  2. Actinomycosis (infection that causes sores, or abscesses)
  3. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  4. Anxiety
  5. Aphthous stomatitis (mouth ulcer)
  6. Blood pressure increased
  7. Bone disorder
  8. Cardiac disorder
  9. Cellulitis (infection under the skin)
  10. Decreased interest

50-59:

  1. Hypotension (abnormally low blood pressure)
  2. Renal failure (kidney dysfunction)
  3. Urinary tract infection
  4. Cytomegalovirus infection
  5. Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
  6. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  7. Post procedural bile leak
  8. Renal failure acute (rapid kidney dysfunction)
  9. Salmonella bacteraemia (infection of blood by salmonella bacteria)
  10. Salmonellosis (an infection with salmonella bacteria)

60+:

  1. Abdominal pain
  2. Actinomycosis (infection that causes sores, or abscesses)
  3. Arthralgia (joint pain)
  4. Blood pressure increased
  5. Bone disorder
  6. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  7. Brain neoplasm (tumour of brain)
  8. Breast mass
  9. Bronchial hyperreactivity
  10. Cardiac disorder

What are the existing conditions these people have? *

  1. Quit Smoking: 11 people, 55.00%
  2. Breast Cancer: 11 people, 55.00%
  3. Bone Neoplasm Malignant (cancer of bone): 10 people, 50.00%
  4. Bone Loss: 7 people, 35.00%
  5. Bone Density Decreased: 4 people, 20.00%
  6. Enterococcal Bacteraemia (presence of bacteria lactic acid in the blood): 2 people, 10.00%
  7. Neoplasm Malignant (cancer tumour): 1 person, 5.00%
  8. High Blood Pressure: 1 person, 5.00%
  9. High Blood Cholesterol: 1 person, 5.00%
  10. Hepatitis C: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Daptomycin and Lidoderm:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Daptomycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lidoderm:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Daptomycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lidoderm and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on daptomycin and lidocaine (the active ingredients of Daptomycin and Lidoderm, respectively), and Daptomycin and Lidoderm (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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