Daptomycin and Oxycontin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Daptomycin (daptomycin) and Oxycontin (oxycodone hydrochloride). Common drug interactions include rash among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Daptomycin and Oxycontin. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Daptomycin?

Daptomycin has active ingredients of daptomycin. eHealthMe is studying from 7,879 Daptomycin users. Check the latest studies of Daptomycin.

What is Oxycontin?

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,533 Oxycontin users. Check the latest studies of Oxycontin.

On Jul, 24, 2026

41 people who take Daptomycin and Oxycontin together, and have interactions are studied.

Daptomycin and Oxycontin drug interactions.

What are the common drug interactions of Daptomycin and Oxycontin, by gender? *:

female:

Rash
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Pulmonary embolism (blockage of the main artery of the lung)
Pyrexia (fever)
General physical health deterioration (weak health status)
Abdominal pain
Acute promyelocytic leukaemia (cancer of the blood and bone marrow)
Anxiety
Bacteraemia (presence of bacteria in the blood)
Blood creatine phosphokinase increased

male:

Pneumonia
Nausea (feeling of having an urge to vomit)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Deformity (disfigurement)
Escherichia sepsis (bacterial infection by escherichia coli)
Failure to thrive (inadequate weight gain and physical growth in children)
Fall
Fatigue (feeling of tiredness)
Gastrointestinal motility disorder (abnormal intestinal contractions)
Haematuria (presence of blood in urine)

What are the common drug interactions of Daptomycin and Oxycontin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal pain
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrioventricular block complete (heart block complete)
Bleeding time prolonged
Chest pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspnoea (difficult or laboured respiration)
Endocarditis (inflammation in heart muscle)
Eosinophilic pneumonia acute (eosinophil accumulates in the lung-acute)

40-49:

Blood calcium decreased
Blood sodium decreased
Blood urea increased
Enterococcus test positive
Hypoxia (low oxygen in tissues)
Intestinal obstruction
Multiple myeloma (cancer of the plasma cells)
Nausea (feeling of having an urge to vomit)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Pericardial effusion (fluid around the heart)

50-59:

Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Salmonella bacteraemia (infection of blood by salmonella bacteria)
Salmonellosis (an infection with salmonella bacteria)
General physical condition
Abdominal pain
Adenovirus infection
Anaphylactic reaction (serious allergic reaction)
Anxiety
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Bacteraemia (presence of bacteria in the blood)

60+:

Pneumonia
Anaemia (lack of blood)
Failure to thrive (inadequate weight gain and physical growth in children)
Fall
Fatigue (feeling of tiredness)
Gastrointestinal motility disorder (abnormal intestinal contractions)
Haematuria (presence of blood in urine)
Hypokalaemia (low potassium)
Immobile (not moving)
Infection

What are the existing conditions these people have? *

Urinary Tract Infection: 5 people, 12.20%
Infection: 5 people, 12.20%
Depression: 4 people, 9.76%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 3 people, 7.32%
Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 7.32%
Osteoporosis (bones weak and more likely to break): 3 people, 7.32%
Oropharyngeal Candidiasis (fungal infection of oropharynx): 3 people, 7.32%
Multiple Myeloma (cancer of the plasma cells): 3 people, 7.32%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 3 people, 7.32%
Hypokalemia (low potassium): 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

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