Daptomycin and Reglan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Daptomycin (daptomycin) and Reglan (metoclopramide hydrochloride). Common drug interactions include injury among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Daptomycin and Reglan. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Daptomycin?

Daptomycin has active ingredients of daptomycin. eHealthMe is studying from 7,879 Daptomycin users. Check the latest studies of Daptomycin.

What is Reglan?

Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.

On Jul, 21, 2026

32 people who take Daptomycin and Reglan together, and have interactions are studied.

Daptomycin and Reglan drug interactions.

What are the common drug interactions of Daptomycin and Reglan, by gender? *:

female:

Injury
International normalised ratio increased
Malaise (a feeling of general discomfort or uneasiness)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Migraine (headache)
Neurological symptom (symptoms of nervous system disease)
Oedema peripheral (superficial swelling)
Pneumonia klebsiella (pneumonia caused by bacteria klebsiella)
Renal failure acute (rapid kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)

male:

Pneumonia
Renal failure acute (rapid kidney dysfunction)
Haematoma (collection of blood outside the blood vessels)
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Hepatic failure (liver failure)
Liver disorder (liver diseases)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Septic shock (shock due to blood infection)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

What are the common drug interactions of Daptomycin and Reglan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Migraine (headache)
Oedema peripheral (superficial swelling)
Pain
Pulmonary embolism (blockage of the main artery of the lung)
Rash
Renal failure (kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)
Septic shock (shock due to blood infection)
Skin disorder (skin disease)

40-49:

Blood pressure fluctuation
Chills (felling of cold)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Enterocolitis haemorrhagic (bleeding and inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
Hypotension (abnormally low blood pressure)
Pulmonary embolism (blockage of the main artery of the lung)
Rectal haemorrhage (bleeding from anus)
Septic shock (shock due to blood infection)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

50-59:

Arrhythmia (irregular heartbeat)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Cardiac failure congestive
Cardiac output decreased
Cardiogenic shock (inadequate circulation of blood)
Cerebellar ischaemia (lack of blood supply to cerebeller)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haematoma (collection of blood outside the blood vessels)
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)

60+:

Pneumonia
Acute respiratory failure
Blood creatine phosphokinase increased
Blood pressure decreased
Endocarditis (inflammation in heart muscle)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Renal tubular necrosis (death of kidney tubules)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)
Sepsis syndrome (a clinical condition of blood infection)

What are the existing conditions these people have? *

Pain: 8 people, 25.00%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 5 people, 15.62%
High Blood Pressure: 5 people, 15.62%
Constipation: 4 people, 12.50%
Nausea (feeling of having an urge to vomit): 4 people, 12.50%
Agitation (state of anxiety or nervous excitement): 4 people, 12.50%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 12.50%
Sedation: 3 people, 9.38%
Rashes (redness): 3 people, 9.38%
Anaemia (lack of blood): 3 people, 9.38%

* Approximation only. Some reports may have incomplete information.

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