Darzalex and Evista drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Darzalex (daratumumab) and Evista (raloxifene hydrochloride). Common drug interactions include lung neoplasm malignant among females.

The phase IV clinical study analyzes what interactions people have when they take Darzalex and Evista. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Darzalex?

Darzalex has active ingredients of daratumumab. eHealthMe is studying from 20,206 Darzalex users. Check the latest studies of Darzalex.

What is Evista?

Evista has active ingredients of raloxifene hydrochloride. It is often used in osteoporosis. eHealthMe is studying from 25,891 Evista users. Check the latest studies of Evista.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 21, 2026

14 people who take Darzalex and Evista together, and have interactions are studied.

Darzalex and Evista drug interactions.

What are the common drug interactions of Darzalex and Evista, by gender? *:

female:

  1. Lung neoplasm malignant (cancer tumour of lung)
  2. Oropharyngeal pain
  3. Back disorder
  4. Blood creatinine increased
  5. Blood potassium decreased
  6. Cardiac disorder
  7. Cataract (clouding of the lens inside the eye)
  8. Depression
  9. Drug intolerance (drug sensitivity)
  10. Electrolyte imbalance

male:

n/a

What are the common drug interactions of Darzalex and Evista, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Back pain
  2. Lung neoplasm malignant (cancer tumour of lung)
  3. Nerve compression
  4. Oropharyngeal pain
  5. Renal impairment (severely reduced kidney function)
  6. Arthralgia (joint pain)
  7. Back disorder
  8. Drug intolerance (drug sensitivity)
  9. Electrolyte imbalance
  10. Fall

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 13 people, 92.86%

* Approximation only. Some reports may have incomplete information.

Do you take Darzalex and Evista?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Darzalex and Evista:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Darzalex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Evista:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Darzalex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Evista and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on daratumumab and raloxifene hydrochloride (the active ingredients of Darzalex and Evista, respectively), and Darzalex and Evista (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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