Daybue and Levocarnitine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Daybue (trofinetide) and Levocarnitine (levocarnitine). Common drug interactions include diarrhoea among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Daybue and Levocarnitine. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Daybue?

Daybue has active ingredients of trofinetide. eHealthMe is studying from 1,959 Daybue users. Check the latest studies of Daybue.

What is Levocarnitine?

Levocarnitine has active ingredients of levocarnitine. It is often used in mitochondrial myopathy. eHealthMe is studying from 3,332 Levocarnitine users. Check the latest studies of Levocarnitine.



On Aug, 02, 2026

38 people who take Daybue and Levocarnitine together, and have interactions are studied.

Daybue and Levocarnitine drug interactions.

What are the common drug interactions of Daybue and Levocarnitine, by gender? *:

female:

  1. Diarrhoea
  2. Vomiting
  3. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  4. Hypersomnia (excessive daytime sleepiness (eds))
  5. Dehydration (dryness resulting from the removal of water)
  6. Hypophagia (reduced food intake)
  7. Constipation
  8. Nausea (feeling of having an urge to vomit)
  9. Retching (strong involuntary effort to vomit)
  10. Secretion discharge

male:

  1. Diarrhoea
  2. Rash
  3. Pneumonia
  4. Fungal infection
  5. Purpura (purplish discoloration of the skin)
  6. Wound
  7. Drug ineffective
  8. Respiratory tract infection
  9. Somnolence (a state of near-sleep, a strong desire for sleep)
  10. Vomiting

What are the common drug interactions of Daybue and Levocarnitine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Diarrhoea
  2. Vomiting
  3. Dehydration (dryness resulting from the removal of water)
  4. Influenza
  5. Hypophagia (reduced food intake)
  6. Drug ineffective
  7. Aggression
  8. Cough
  9. Fatigue (feeling of tiredness)
  10. Pyrexia (fever)

10-19:

  1. Diarrhoea
  2. Hypersomnia (excessive daytime sleepiness (eds))
  3. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  4. Vomiting
  5. Abdominal discomfort
  6. Nausea (feeling of having an urge to vomit)
  7. Adverse drug reaction
  8. Hypophagia (reduced food intake)
  9. Pneumonia
  10. Vomiting projectile

20-29:

  1. Constipation
  2. Abnormal behaviour
  3. Blood potassium decreased
  4. Dehydration (dryness resulting from the removal of water)
  5. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  6. Hypophagia (reduced food intake)
  7. Weight bearing difficulty (difficulty due to weight of thigh fat deposition)
  8. Sleep terror (felling of terror in sleep)
  9. Abnormal faeces (abnormal stool)
  10. Dermatitis diaper (diaper rash is a common form of inflamed skin)

30-39:

  1. Diarrhoea
  2. Rash
  3. Fungal infection
  4. Pneumonia
  5. Purpura (purplish discoloration of the skin)
  6. Wound

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Hypersensitivity: 8 people, 21.05%
  2. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 13.16%
  3. Constipation: 4 people, 10.53%
  4. Pain: 3 people, 7.89%
  5. Fever: 3 people, 7.89%
  6. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 3 people, 7.89%
  7. Seasonal Allergy (allergic condition due to certain season): 2 people, 5.26%
  8. Nausea And Vomiting: 2 people, 5.26%
  9. Nausea (feeling of having an urge to vomit): 2 people, 5.26%
  10. Menstrual Disorder (disease of menstrual cycle): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Daybue and Levocarnitine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Daybue:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Levocarnitine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Daybue and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levocarnitine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on trofinetide and levocarnitine (the active ingredients of Daybue and Levocarnitine, respectively), and Daybue and Levocarnitine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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