Daypro and Plavix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Daypro (oxaprozin) and Plavix (clopidogrel bisulfate). Common drug interactions include chest pain among females and hyperlipidaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Daypro and Plavix. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Daypro?

Daypro has active ingredients of oxaprozin. It is often used in osteoarthritis. eHealthMe is studying from 2,883 Daypro users. Check the latest studies of Daypro.

What is Plavix?

Plavix has active ingredients of clopidogrel bisulfate. It is often used in stent. eHealthMe is studying from 151,178 Plavix users. Check the latest studies of Plavix.



On Jul, 12, 2026

59 people who take Daypro and Plavix together, and have interactions are studied.

Daypro and Plavix drug interactions.

What are the common drug interactions of Daypro and Plavix, by gender? *:

female:

  1. Chest pain
  2. Hepatic enzyme increased
  3. Hypokalaemia (low potassium)
  4. Pulmonary oedema (fluid accumulation in the lungs)
  5. Respiratory failure (inadequate gas exchange by the respiratory system)
  6. Blood pressure increased
  7. Syncope (loss of consciousness with an inability to maintain postural tone)
  8. Syncope vasovagal (malfunction in the parts of the nervous system leads to consciousness with an inability to maintain postural tone)
  9. Depression
  10. Gout (uric acid crystals building up in the body)

male:

  1. Hyperlipidaemia (presence of excess lipids in the blood)
  2. Cardiac failure congestive
  3. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  4. Gout (uric acid crystals building up in the body)
  5. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  6. Rhinitis allergic (inflammation of the nasal airways due to allergy)
  7. Acute myocardial infarction (acute heart attack)
  8. Anaemia (lack of blood)
  9. Anxiety
  10. Bronchitis acute (acute inflammation of the mucous membrane in the bronchial tubes)

What are the common drug interactions of Daypro and Plavix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chest pain
  2. Dyspnoea (difficult or laboured respiration)
  3. Abdominal pain
  4. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  5. Acute myocardial infarction (acute heart attack)
  6. Anaemia (lack of blood)
  7. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  8. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  9. Blood glucose increased
  10. Blood pressure increased

50-59:

  1. Hypercholesterolaemia (high levels of cholesterol in the blood)
  2. Syncope (loss of consciousness with an inability to maintain postural tone)
  3. Chronic obstructive airways disease
  4. Palpitations (feelings or sensations that your heart is pounding or racing)
  5. Cardiomyopathy (weakening of the heart muscle)
  6. Dizziness
  7. Hypertensive heart disease
  8. Activities of daily living impaired
  9. Anxiety
  10. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

60+:

  1. Diarrhoea
  2. Chest pain
  3. Cardiac failure congestive
  4. Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
  5. Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
  6. Cervix inflammation
  7. Cluster headache (one-sided head pain with tearing)
  8. Decreased immune responsiveness
  9. Depression
  10. Dihydrotestosterone decreased

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 22 people, 37.29%
  2. High Blood Pressure: 18 people, 30.51%
  3. Sleep Disorder: 11 people, 18.64%
  4. Gastric Ulcer (stomach ulcer): 10 people, 16.95%
  5. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 10 people, 16.95%
  6. Allergic Rhinitis: 10 people, 16.95%
  7. Depression: 8 people, 13.56%
  8. Insomnia (sleeplessness): 5 people, 8.47%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 8.47%
  10. Joint Pain: 4 people, 6.78%

* Approximation only. Some reports may have incomplete information.

Do you take Daypro and Plavix?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Daypro and Plavix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Daypro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Plavix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Daypro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Plavix and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on oxaprozin and clopidogrel bisulfate (the active ingredients of Daypro and Plavix, respectively), and Daypro and Plavix (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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