Ddavp and Ondansetron drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ddavp (desmopressin acetate) and Ondansetron (ondansetron). Common drug interactions include atelectasis among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Ddavp and Ondansetron. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Ddavp?

Ddavp has active ingredients of desmopressin acetate. It is often used in diabetes insipidus. eHealthMe is studying from 2,614 Ddavp users. Check the latest studies of Ddavp.

What is Ondansetron?

Ondansetron has active ingredients of ondansetron. It is often used in nausea. eHealthMe is studying from 122,738 Ondansetron users. Check the latest studies of Ondansetron.



On Jul, 13, 2026

24 people who take Ddavp and Ondansetron together, and have interactions are studied.

Ddavp and Ondansetron drug interactions.

What are the common drug interactions of Ddavp and Ondansetron, by gender? *:

female:

  1. Atelectasis (partial or complete collapse of the lung)
  2. Hypernatraemia (an abnormally high plasma concentration of sodium ions)
  3. Hypertension (high blood pressure)
  4. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  5. Hypokalaemia (low potassium)
  6. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  7. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  8. Lung consolidation (a condition whereby the lung tissues solidify because of the accumulation of solid and liquid material in the air spaces)
  9. Mucosal inflammation (infection of mucous membrane)
  10. Stomatitis (inflammation of mucous membrane of mouth)

male:

  1. Pain
  2. Decreased appetite
  3. Emotional distress
  4. Renal failure (kidney dysfunction)
  5. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  6. Dehydration (dryness resulting from the removal of water)
  7. Depression
  8. Fear of disease
  9. Hypernatraemia (an abnormally high plasma concentration of sodium ions)
  10. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

What are the common drug interactions of Ddavp and Ondansetron, by age (0-1 to 60+)? *:

0-1:

  1. Decreased appetite
  2. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  3. Myoclonic epilepsy (type of epilepsy with quick little jerks of the arms, shoulder, or occasionally the legs)
  4. Pain
  5. Constipation
  6. Muscle spasms (muscle contraction)
  7. Dehydration (dryness resulting from the removal of water)
  8. Hypernatraemia (an abnormally high plasma concentration of sodium ions)
  9. Hypoglycaemia (deficiency of glucose in the bloodstream)
  10. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)

2-9:

  1. Blood sodium decreased
  2. Grand mal convulsion (a type of generalized seizure that affects the entire brain)

10-19:

  1. Influenza like illness
  2. Atelectasis (partial or complete collapse of the lung)
  3. Hypernatraemia (an abnormally high plasma concentration of sodium ions)
  4. Hypertension (high blood pressure)
  5. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  6. Hypokalaemia (low potassium)
  7. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  8. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  9. Lung consolidation (a condition whereby the lung tissues solidify because of the accumulation of solid and liquid material in the air spaces)
  10. Mucosal inflammation (infection of mucous membrane)

20-29:

  1. Abortion spontaneous (naturally occurring miscarriage)
  2. Drug hypersensitivity

30-39:

n/a

40-49:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Chronic kidney disease
  4. Emotional distress
  5. Pain
  6. Renal failure (kidney dysfunction)
  7. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  8. Depression
  9. Fear of disease
  10. Blood creatinine increased

50-59:

  1. Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
  2. Chest discomfort
  3. Dyspnoea (difficult or laboured respiration)
  4. Feeling cold
  5. Headache (pain in head)
  6. Myalgia (muscle pain)

60+:

  1. Abdominal distension
  2. Abdominal pain
  3. Pleural effusion (water on the lungs)
  4. Renal haematoma (blood collection in kidney)
  5. Sleep disorder
  6. Streptococcal urinary tract infection (a bacterial infection of urinary tract)
  7. Urinoma (a collection of extravasated urine)
  8. Blood bilirubin increased
  9. Blood urea increased
  10. Fall

What are the existing conditions these people have? *

  1. Pain: 6 people, 25.00%
  2. Nausea And Vomiting: 5 people, 20.83%
  3. Constipation: 4 people, 16.67%
  4. Fever: 4 people, 16.67%
  5. Infantile Spasms: 3 people, 12.50%
  6. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 3 people, 12.50%
  7. Venipuncture: 2 people, 8.33%
  8. Hypernatraemia (an abnormally high plasma concentration of sodium ions): 2 people, 8.33%
  9. Lower Respiratory Tract Infection: 2 people, 8.33%
  10. Itching: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ddavp and Ondansetron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ddavp:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ondansetron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ddavp and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ondansetron and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on desmopressin acetate and ondansetron (the active ingredients of Ddavp and Ondansetron, respectively), and Ddavp and Ondansetron (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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