Ddavp and Zyprexa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ddavp (desmopressin acetate) and Zyprexa (olanzapine). Common drug interactions include drug ineffective among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Ddavp and Zyprexa. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Ddavp?

Ddavp has active ingredients of desmopressin acetate. It is often used in diabetes insipidus. eHealthMe is studying from 2,614 Ddavp users. Check the latest studies of Ddavp.

What is Zyprexa?

Zyprexa has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 64,724 Zyprexa users. Check the latest studies of Zyprexa.



On Jul, 13, 2026

26 people who take Ddavp and Zyprexa together, and have interactions are studied.

Ddavp and Zyprexa drug interactions.

What are the common drug interactions of Ddavp and Zyprexa, by gender? *:

female:

  1. Drug ineffective
  2. Abdominal pain upper
  3. Intestinal obstruction
  4. Acute myocardial infarction (acute heart attack)
  5. Asthenia (weakness)
  6. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  7. Confusion
  8. Death
  9. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  10. Dysarthria (speech disorder)

male:

  1. Drug ineffective
  2. Blood glucose increased
  3. Suicide attempt
  4. Type 2 diabetes mellitus
  5. Urinary retention (the inability to completely or partially empty the bladder)
  6. Urine ketone body present
  7. Aggression
  8. Agitation (state of anxiety or nervous excitement)
  9. Asthenia (weakness)
  10. Benign prostatic hyperplasia (benign enlargement of the prostate)

What are the common drug interactions of Ddavp and Zyprexa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Blood glucose increased
  2. Diabetes mellitus insulin-dependent
  3. Drug ineffective
  4. Nausea (feeling of having an urge to vomit)
  5. Urine ketone body present
  6. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  7. Hyperglycaemia (high blood sugar)
  8. Metabolic disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues)
  9. Weight increased

10-19:

  1. Bradycardia (abnormally slow heart action)
  2. Sedation
  3. Abdominal pain upper
  4. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  5. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  6. Drug ineffective
  7. Dry mouth
  8. Fatigue (feeling of tiredness)
  9. Headache (pain in head)
  10. Heart rate decreased

20-29:

n/a

30-39:

n/a

40-49:

  1. Intestinal obstruction
  2. Urinary retention (the inability to completely or partially empty the bladder)
  3. Asthenia (weakness)
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  5. Confusion
  6. Death
  7. Dry mouth
  8. Dysuria (painful or difficult urination)
  9. Gastrointestinal injury (injury to gastrointestinal tract)
  10. Headache (pain in head)

50-59:

  1. Abdominal pain upper
  2. Aggression
  3. Agitation (state of anxiety or nervous excitement)
  4. Benign prostatic hyperplasia (benign enlargement of the prostate)
  5. Blood urine present
  6. Chills (felling of cold)
  7. Drug ineffective
  8. Dysarthria (speech disorder)
  9. Dysuria (painful or difficult urination)
  10. Fall

60+:

  1. Acute myocardial infarction (acute heart attack)
  2. Asthenia (weakness)
  3. Dyspnoea (difficult or laboured respiration)
  4. Hallucination (an experience involving the perception of something not present)
  5. Hypotension (abnormally low blood pressure)
  6. Nephrogenic diabetes insipidus (a disorder in which a defect in the small tubes (tubules) in the kidneys causes a person to pass a large amount of urine)
  7. Pulmonary embolism (blockage of the main artery of the lung)
  8. Sedation
  9. Sepsis (a severe blood infection that can lead to organ failure and death)
  10. Urinary incontinence (inability to control the flow of urine and involuntary urination)

What are the existing conditions these people have? *

  1. Wheezing (a high-pitched whistling sound made while you breath): 2 people, 7.69%
  2. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 7.69%
  3. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 7.69%
  4. Itching: 2 people, 7.69%
  5. Bedwetting: 2 people, 7.69%
  6. Affective Disorder (mental disorder): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Ddavp and Zyprexa?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ddavp and Zyprexa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ddavp:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zyprexa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ddavp and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zyprexa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on desmopressin acetate and olanzapine (the active ingredients of Ddavp and Zyprexa, respectively), and Ddavp and Zyprexa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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