Decadron and Glucovance drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Decadron (dexamethasone) and Glucovance (glyburide; metformin hydrochloride). Common drug interactions include depression among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Decadron and Glucovance. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Decadron?

Decadron has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 47,210 Decadron users. Check the latest studies of Decadron.

What is Glucovance?

Glucovance has active ingredients of glyburide; metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 6,302 Glucovance users. Check the latest studies of Glucovance.



On Jul, 15, 2026

49 people who take Decadron and Glucovance together, and have interactions are studied.

Decadron and Glucovance drug interactions.

What are the common drug interactions of Decadron and Glucovance, by gender? *:

female:

  1. Depression
  2. Dizziness
  3. Upper respiratory tract infection
  4. Oedema peripheral (superficial swelling)
  5. Pain
  6. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  7. Oral disorder (mouth disease)
  8. Back pain
  9. Fall
  10. Headache (pain in head)

male:

  1. Fall
  2. Asthenia (weakness)
  3. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  4. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  5. Pneumonia
  6. Anaemia (lack of blood)
  7. Balance disorder
  8. Chest pain
  9. Dehydration (dryness resulting from the removal of water)
  10. Dizziness

What are the common drug interactions of Decadron and Glucovance, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Asthenia (weakness)
  2. Abasia (inability to walk)
  3. Arthralgia (joint pain)
  4. Back pain
  5. Bone disorder
  6. Breast cellulitis (spreading, acute inflammation of beast skin)
  7. Diarrhoea
  8. Dyspnoea (difficult or laboured respiration)
  9. Extravasation (leakage of a fluid)
  10. Fall

50-59:

  1. Cardiomyopathy (weakening of the heart muscle)
  2. Death
  3. Dyspnoea (difficult or laboured respiration)
  4. Family stress
  5. Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
  6. Multiple injuries
  7. Acute myocardial infarction (acute heart attack)
  8. Angina pectoris (chest pain due to ischemia of the heart muscle)
  9. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  10. Anxiety

60+:

  1. Anxiety
  2. Injury
  3. Balance disorder
  4. Pyrexia (fever)
  5. Weight decreased
  6. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  7. Depression
  8. Fatigue (feeling of tiredness)
  9. Headache (pain in head)
  10. Oedema peripheral (superficial swelling)

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 8 people, 16.33%
  2. Neoplasm Malignant (cancer tumour): 8 people, 16.33%
  3. Metastases To Bone (cancer spreads to bone): 8 people, 16.33%
  4. Osteolysis (dissolution of bone): 5 people, 10.20%
  5. Resorption Bone Increased: 4 people, 8.16%

* Approximation only. Some reports may have incomplete information.

Do you take Decadron and Glucovance?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Decadron and Glucovance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Decadron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Glucovance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Decadron and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Glucovance and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on dexamethasone and glyburide; metformin hydrochloride (the active ingredients of Decadron and Glucovance, respectively), and Decadron and Glucovance (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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