Decadron and Iclusig drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Decadron (dexamethasone) and Iclusig (ponatinib hydrochloride). Common drug interactions include hospitalisation among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Decadron and Iclusig. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Decadron?

Decadron has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 47,210 Decadron users. Check the latest studies of Decadron.

What is Iclusig?

Iclusig has active ingredients of ponatinib hydrochloride. eHealthMe is studying from 6,109 Iclusig users. Check the latest studies of Iclusig.

On Jul, 13, 2026

14 people who take Decadron and Iclusig together, and have interactions are studied.

What are the common drug interactions of Decadron and Iclusig, by gender? *:

female:

Hospitalisation
Pyrexia (fever)
White blood cell count decreased
Abdominal pain
Asthenia (weakness)
Blast cell count increased
Chemotherapy
Fatigue (feeling of tiredness)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Haemoglobin decreased

male:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Peripheral swelling
Ventricular hypokinesia (muscle of one's heart does not contract as much as most peoples' hearts do)
Neutropenia (an abnormally low number of neutrophils)
Fall
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombocytopenia (decrease of platelets in blood)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

What are the common drug interactions of Decadron and Iclusig, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Blood immunoglobulin g decreased
Blood magnesium decreased
Cough
Haematocrit decreased
Haemoglobin decreased
Nasopharyngitis (inflammation of the nasopharynx)
Pancreatitis (inflammation of pancreas)

40-49:

Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Bone pain
Troponin i increased

50-59:

Abdominal pain
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blast cell count increased
Bone marrow necrosis (death of body tissue of bone marrow)
Death
Dysphagia (a condition in which swallowing is difficult or painful)
Encephalitis (inflammation of the brain)
Flat affect (absence of emotional response to a situation)
Hypoxia (low oxygen in tissues)
Muscle atrophy (a decrease in the mass of the muscle)

60+:

Abdominal pain
Asthenia (weakness)
Splenomegaly (enlargement of spleen)
White blood cell count increased
Blood glucose increased
Fall
Pyrexia (fever)
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombocytopenia (decrease of platelets in blood)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 7 people, 50.00%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 4 people, 28.57%
Pain: 4 people, 28.57%
Depression: 2 people, 14.29%
Nausea And Vomiting: 2 people, 14.29%
Nausea (feeling of having an urge to vomit): 2 people, 14.29%
High Blood Pressure: 2 people, 14.29%
Abdominal Pain: 1 person, 7.14%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 1 person, 7.14%
Bone Disorder: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Decadron and Iclusig?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously