Deferasirox and Hydramine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Deferasirox (deferasirox) and Hydramine (diphenhydramine hydrochloride). Common drug interactions include constipation among females and sepsis among males.

The phase IV clinical study analyzes what interactions people have when they take Deferasirox and Hydramine. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Deferasirox?

Deferasirox has active ingredients of deferasirox. eHealthMe is studying from 2,641 Deferasirox users. Check the latest studies of Deferasirox.

What is Hydramine?

Hydramine has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 114,900 Hydramine users. Check the latest studies of Hydramine.

On Jul, 18, 2026

32 people who take Deferasirox and Hydramine together, and have interactions are studied.

Deferasirox and Hydramine drug interactions.

What are the common drug interactions of Deferasirox and Hydramine, by gender? *:

female:

Constipation
Pneumonia
Arthralgia (joint pain)
Cerebral haemorrhage (bleeding within the brain)
Cytomegalovirus chorioretinitis (infection of choroid and retina of the eye from virus)
Hospitalisation
Periorbital haematoma (collection of blood around the eyes)
Death
Adenovirus infection
Adverse drug reaction

male:

Sepsis (a severe blood infection that can lead to organ failure and death)
Arthralgia (joint pain)
Platelet count decreased
Pyrexia (fever)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Blast crisis in myelogenous leukaemia
Constipation
General physical condition
Fall
Head injury

What are the common drug interactions of Deferasirox and Hydramine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Adenovirus infection

30-39:

Adverse drug reaction
Anaemia (lack of blood)
Headache (pain in head)
Loss of consciousness
Nausea (feeling of having an urge to vomit)
Pain
Pneumonia
Throat irritation
Vomiting

40-49:

Hospitalisation
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood bilirubin increased
Blood glucose increased
Blood lactate dehydrogenase increased
Epigastric discomfort
Haematocrit decreased
Haemoglobin decreased
Haptoglobin decreased

50-59:

Arthralgia (joint pain)
Cerebral haemorrhage (bleeding within the brain)
Cytomegalovirus chorioretinitis (infection of choroid and retina of the eye from virus)
Periorbital haematoma (collection of blood around the eyes)
Pneumonia
Constipation
Death
Pyrexia (fever)
Blast crisis in myelogenous leukaemia
General physical condition

60+:

Lung infection
Sepsis (a severe blood infection that can lead to organ failure and death)
Chest pain
Constipation
Delirium (wild excitement)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Duodenal ulcer haemorrhage (bleeding duodenal ulcer)
Dyspnoea (difficult or laboured respiration)
Febrile neutropenia (fever with reduced white blood cells)
Graft versus host disease in intestine (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body and damages intestinal mucosal membrane)

What are the existing conditions these people have? *

Constipation: 8 people, 25.00%
Iron Overload: 6 people, 18.75%
Aplastic Anemia: 6 people, 18.75%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 5 people, 15.62%
Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 4 people, 12.50%
Haemochromatosis (body to absorb more iron than usual from food): 4 people, 12.50%
Pain: 3 people, 9.38%
High Blood Pressure: 3 people, 9.38%
Enlarged Prostate: 3 people, 9.38%
Diarrhea: 3 people, 9.38%

* Approximation only. Some reports may have incomplete information.

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