Defitelio and Mycamine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Defitelio (defibrotide sodium) and Mycamine (micafungin sodium). Common drug interactions include pleural effusion among females and pulmonary haemorrhage among males.
The phase IV clinical study analyzes what interactions people have when they take Defitelio and Mycamine. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Defitelio?
Defitelio has active ingredients of defibrotide sodium. eHealthMe is studying from 4,343 Defitelio users. Check the latest studies of Defitelio.
What is Mycamine?
Mycamine has active ingredients of micafungin sodium. eHealthMe is studying from 2,237 Mycamine users. Check the latest studies of Mycamine.
17 people who take Defitelio and Mycamine together, and have interactions are studied.

What are the common drug interactions of Defitelio and Mycamine, by gender? *:
female:
- Pleural effusion (water on the lungs)
- Haematemesis (vomiting of blood)
- Haematochezia (passage of stools containing blood)
- Melaena (the passage of black, tarry stools)
- Oedema (fluid collection in tissue)
- Pericardial effusion (fluid around the heart)
- Peritoneal haemorrhage (peritoneal bleeding)
male:
- Pulmonary haemorrhage (acute bleeding from the lung)
- Renal haematoma (blood collection in kidney)
- Hypophagia (reduced food intake)
- Pericardial effusion (fluid around the heart)
- Pleural effusion (water on the lungs)
- Pulmonary oedema (fluid accumulation in the lungs)
- Vasculitis (inflammation of a blood vessel or blood vessels)
- Cardiogenic shock (inadequate circulation of blood)
- Pneumonia
- Pneumonia adenoviral (viral pneumonia caused by an adenovirus)
What are the common drug interactions of Defitelio and Mycamine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Pulmonary haemorrhage (acute bleeding from the lung)
- Renal haematoma (blood collection in kidney)
- Pulmonary interstitial emphysema syndrome (collection of gases outside of the normal air passages and inside the connective tissue of the peribronchovascular sheaths, interlobular septa, and visceral pleura of lungs)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Urinary bladder haemorrhage (urinary bladder bleeding)
- Haematemesis (vomiting of blood)
- Haematochezia (passage of stools containing blood)
- Melaena (the passage of black, tarry stools)
- Pleural effusion (water on the lungs)
10-19:
- Pericardial effusion (fluid around the heart)
- Pleural effusion (water on the lungs)
- Bk virus infection
- Blood creatinine increased
- Cystitis haemorrhagic (blood in the urine and painful voiding)
- Cytomegalovirus infection
- Dehydration (dryness resulting from the removal of water)
- Haematuria (presence of blood in urine)
- Hypertension (high blood pressure)
- Hypophagia (reduced food intake)
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
n/a
What are the existing conditions these people have? *
- Venoocclusive Disease (small veins in the liver are obstructed): 14 people, 82.35%
- Stress And Anxiety: 5 people, 29.41%
- High Blood Pressure: 5 people, 29.41%
- Abdominal Pain: 3 people, 17.65%
- Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 3 people, 17.65%
- Sedation: 3 people, 17.65%
- Hypokalemia (low potassium): 3 people, 17.65%
- Infection: 3 people, 17.65%
- Eczema Herpeticum (feverish condition and widespread eruption of vesicles): 2 people, 11.76%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.76%
* Approximation only. Some reports may have incomplete information.
Do you take Defitelio and Mycamine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Defitelio and Mycamine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Defitelio:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Mycamine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Defitelio and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Mycamine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Cheng HI, Chen TH, Chung TC, Lee HY, Yu CY, "Micafungin-Induced Hyperbilirubinemia: A Case Report", 臺灣臨床藥學雜誌, 2014 Jun .
- Cheng HI, Chen TH, Chung TC, Lee HY, Yu CY, "Micafungin-Induced Hyperbilirubinemia: A Case Report", 臺灣臨床藥學雜誌, 2014 Jun .
How the study uses the data?
The study uses data from the FDA. It is based on defibrotide sodium and micafungin sodium (the active ingredients of Defitelio and Mycamine, respectively), and Defitelio and Mycamine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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