Defitelio and Prevymis drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Defitelio (defibrotide sodium) and Prevymis (letermovir). Common drug interactions include abdominal pain among females and acute myeloid leukaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Defitelio and Prevymis. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Defitelio?

Defitelio has active ingredients of defibrotide sodium. eHealthMe is studying from 4,343 Defitelio users. Check the latest studies of Defitelio.

What is Prevymis?

Prevymis has active ingredients of letermovir. eHealthMe is studying from 1,328 Prevymis users. Check the latest studies of Prevymis.

On Jul, 11, 2026

24 people who take Defitelio and Prevymis together, and have interactions are studied.

Defitelio and Prevymis drug interactions.

What are the common drug interactions of Defitelio and Prevymis, by gender? *:

female:

Abdominal pain
Acute respiratory distress syndrome
Death

male:

Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Cerebral haemorrhage (bleeding within the brain)
Chronic kidney disease
Cystitis haemorrhagic (blood in the urine and painful voiding)
Drug ineffective
Hypotension (abnormally low blood pressure)
Venoocclusive liver disease (small veins in the liver are obstructed)
Adult t-cell lymphoma/leukaemia (cancer of the immune system's own t-cells)
Pulmonary alveolar haemorrhage (acute bleeding)
Respiratory failure (inadequate gas exchange by the respiratory system)

What are the common drug interactions of Defitelio and Prevymis, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Drug ineffective
Hypotension (abnormally low blood pressure)
Venoocclusive liver disease (small veins in the liver are obstructed)
Abdominal pain
Acute respiratory distress syndrome
Death
Chronic kidney disease

60+:

Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Cerebral haemorrhage (bleeding within the brain)
Cystitis haemorrhagic (blood in the urine and painful voiding)
Adult t-cell lymphoma/leukaemia (cancer of the immune system's own t-cells)
Pulmonary alveolar haemorrhage (acute bleeding)
Respiratory failure (inadequate gas exchange by the respiratory system)

What are the existing conditions these people have? *

Febrile Bone Marrow Aplasia (bone marrow greatly decreases or stops production of blood cells): 16 people, 66.67%
Venoocclusive Disease (small veins in the liver are obstructed): 15 people, 62.50%
Pain: 15 people, 62.50%
Nausea (feeling of having an urge to vomit): 15 people, 62.50%
High Blood Pressure: 15 people, 62.50%
Fungal Infection: 15 people, 62.50%
Blood Disorder: 15 people, 62.50%
Abdominal Pain Upper: 15 people, 62.50%
Venoocclusive Liver Disease (small veins in the liver are obstructed): 8 people, 33.33%

* Approximation only. Some reports may have incomplete information.

Do you take Defitelio and Prevymis?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously