Deltasone and Vioxx drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Deltasone (prednisone) and Vioxx (rofecoxib). Common drug interactions include anxiety among females and hypertension among males.

The phase IV clinical study analyzes what interactions people have when they take Deltasone and Vioxx. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Deltasone?

Deltasone has active ingredients of prednisone. eHealthMe is studying from 4,243 Deltasone users. Check the latest studies of Deltasone.

What is Vioxx?

Vioxx has active ingredients of rofecoxib. It is often used in arthritis. eHealthMe is studying from 110,130 Vioxx users. Check the latest studies of Vioxx.

On Jul, 17, 2026

58 people who take Deltasone and Vioxx together, and have interactions are studied.

What are the common drug interactions of Deltasone and Vioxx, by gender? *:

female:

Anxiety
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Constipation
Cardiac failure
Chest pain
Hyperkeratosis (thickening of the outer layer of the skin)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nausea (feeling of having an urge to vomit)
Spinal compression fracture (fracture due to spinal compression on bone)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))

male:

Hypertension (high blood pressure)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pulmonary oedema (fluid accumulation in the lungs)
Atelectasis (partial or complete collapse of the lung)
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Depression
Dyspnoea (difficult or laboured respiration)
Fall
Hyperlipidaemia (presence of excess lipids in the blood)
Hypotension (abnormally low blood pressure)

What are the common drug interactions of Deltasone and Vioxx, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hypertension (high blood pressure)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Obesity (having too much body fat)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Abdominal mass (localized enlargement or swelling in the human abdomen)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood bilirubin increased
Cardiac arrest
Cardiac disorder

40-49:

Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Hypertension (high blood pressure)
Hyperlipidaemia (presence of excess lipids in the blood)
Acute myocardial infarction (acute heart attack)
Atelectasis (partial or complete collapse of the lung)
Chest pain
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Depression

50-59:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Oedema peripheral (superficial swelling)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Chest pain
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Fall
Aggression
Anxiety
Appendicitis (inflammation of the appendix)

60+:

Depression
Dyspnoea (difficult or laboured respiration)
Weight decreased
Anaemia (lack of blood)
Balance disorder
Death
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Dry skin
Haematochezia (passage of stools containing blood)
Haemorrhage (bleeding)

What are the existing conditions these people have? *

Depression: 9 people, 15.52%
Glaucoma (increased fluid pressure in the eye with vision loss): 8 people, 13.79%
Asthma: 7 people, 12.07%
High Blood Pressure: 6 people, 10.34%
Osteoporosis (bones weak and more likely to break): 6 people, 10.34%
Facial Nerve Disorder (disease of face nerve): 6 people, 10.34%
Pain: 5 people, 8.62%
Insomnia (sleeplessness): 5 people, 8.62%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 8.62%
Stress And Anxiety: 4 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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