Demadex and Multaq drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Demadex (torsemide) and Multaq (dronedarone hydrochloride). Common drug interactions include dyspnoea among females and coagulopathy among males.

The phase IV clinical study analyzes what interactions people have when they take Demadex and Multaq. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Demadex?

Demadex has active ingredients of torsemide. It is often used in heart failure. eHealthMe is studying from 5,358 Demadex users. Check the latest studies of Demadex.

What is Multaq?

Multaq has active ingredients of dronedarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 11,053 Multaq users. Check the latest studies of Multaq.



On Jul, 08, 2026

23 people who take Demadex and Multaq together, and have interactions are studied.

Demadex and Multaq drug interactions.

What are the common drug interactions of Demadex and Multaq, by gender? *:

female:

  1. Dyspnoea (difficult or laboured respiration)
  2. Weight increased
  3. Fatigue (feeling of tiredness)
  4. Cardiac failure congestive
  5. Alopecia (absence of hair from areas of the body)
  6. Glossodynia (a burning or painful sensation in the tongue)
  7. Pruritus (severe itching of the skin)
  8. Abdominal distension
  9. Fluid retention (an abnormal accumulation of fluid in the blood)
  10. Joint swelling

male:

  1. Coagulopathy (blood's ability to clot is impaired)
  2. Excoriation (to tear or wear off the skin of)
  3. Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
  4. Cardiac failure
  5. Cardiac failure congestive
  6. Death
  7. Dyspnoea (difficult or laboured respiration)
  8. Ejection fraction decreased (systolic heart failure)
  9. Oedema peripheral (superficial swelling)
  10. Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)

What are the common drug interactions of Demadex and Multaq, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal pain upper
  2. Blood potassium decreased
  3. Cardiac failure congestive
  4. Dyspnoea (difficult or laboured respiration)
  5. Ejection fraction decreased (systolic heart failure)
  6. Flatulence (flatus expelled through the anus)
  7. Gait disturbance
  8. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  9. Weight increased
  10. Oedema (fluid collection in tissue)

50-59:

n/a

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Fluid retention (an abnormal accumulation of fluid in the blood)
  3. Coagulopathy (blood's ability to clot is impaired)
  4. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  5. Cardiac failure congestive
  6. Cardiac arrest
  7. Tremor (trembling or shaking movements in one or more parts of your body)
  8. Blood creatinine increased
  9. Excoriation (to tear or wear off the skin of)
  10. Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

  1. Wheezing (a high-pitched whistling sound made while you breath): 3 people, 13.04%
  2. Weight Increased: 3 people, 13.04%
  3. Type 2 Diabetes: 3 people, 13.04%
  4. Oedema (fluid collection in tissue): 3 people, 13.04%
  5. Diabetes: 3 people, 13.04%
  6. Breast Cancer Metastatic: 3 people, 13.04%
  7. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 8.70%
  8. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 8.70%
  9. Cardiac Flutter (abnormal heart rhythm): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Demadex and Multaq?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Demadex and Multaq:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Demadex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Multaq:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Demadex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Multaq and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on torsemide and dronedarone hydrochloride (the active ingredients of Demadex and Multaq, respectively), and Demadex and Multaq (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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