Demadex and Velcade drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Demadex (torsemide) and Velcade (bortezomib). Common drug interactions include full blood count decreased among females and weight increased among males.

The phase IV clinical study analyzes what interactions people have when they take Demadex and Velcade. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Demadex?

Demadex has active ingredients of torsemide. It is often used in heart failure. eHealthMe is studying from 5,358 Demadex users. Check the latest studies of Demadex.

What is Velcade?

Velcade has active ingredients of bortezomib. It is often used in multiple myeloma. eHealthMe is studying from 66,422 Velcade users. Check the latest studies of Velcade.



On Jul, 23, 2026

26 people who take Demadex and Velcade together, and have interactions are studied.

Demadex and Velcade drug interactions.

What are the common drug interactions of Demadex and Velcade, by gender? *:

female:

  1. Full blood count decreased
  2. Pyrexia (fever)
  3. Ataxia (loss of full control of bodily movements)
  4. Blood glucose increased
  5. Breast cancer
  6. Cardiac failure congestive
  7. Cardiomegaly (increased size of heart than normal)
  8. Cerebellar haemorrhage (bleeding in cerebeller)
  9. Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)
  10. Cerebral ventricle dilatation (enlargement of ventricle of brain)

male:

  1. Weight increased
  2. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  3. Dyspnoea (difficult or laboured respiration)
  4. Fluid retention (an abnormal accumulation of fluid in the blood)
  5. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  6. Asthenia (weakness)
  7. Cardiac failure
  8. Cardiac output decreased
  9. Haemorrhage (bleeding)
  10. Hodgkin's disease (cancer originating from white blood cells)

What are the common drug interactions of Demadex and Velcade, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Cough
  2. Pain
  3. Pyrexia (fever)

40-49:

n/a

50-59:

  1. Ataxia (loss of full control of bodily movements)
  2. Breast cancer
  3. Cardiac failure congestive
  4. Cardiomegaly (increased size of heart than normal)
  5. Cerebellar haemorrhage (bleeding in cerebeller)
  6. Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)
  7. Cerebral ventricle dilatation (enlargement of ventricle of brain)
  8. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  9. Colonic polyp (extra part of colon tissue grow in intestine)
  10. Colonoscopy

60+:

  1. Weight increased
  2. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  3. Dyspnoea (difficult or laboured respiration)
  4. Fluid retention (an abnormal accumulation of fluid in the blood)
  5. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  6. Asthenia (weakness)
  7. Cardiac failure
  8. Cardiac output decreased
  9. Haemorrhage (bleeding)
  10. Hodgkin's disease (cancer originating from white blood cells)

What are the existing conditions these people have? *

  1. Pulmonary Hypertension (increase in blood pressure in the lung artery): 7 people, 26.92%
  2. Cardiac Failure: 5 people, 19.23%
  3. Urination - Excessive At Night: 4 people, 15.38%
  4. Type 2 Diabetes: 4 people, 15.38%
  5. High Blood Cholesterol: 4 people, 15.38%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 15.38%
  7. Blood Testosterone Decreased: 4 people, 15.38%
  8. Arrhythmias (irregular heartbeat): 4 people, 15.38%
  9. Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 11.54%
  10. Wheezing (a high-pitched whistling sound made while you breath): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Demadex and Velcade?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Demadex and Velcade:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Demadex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Velcade:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Demadex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Velcade and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on torsemide and bortezomib (the active ingredients of Demadex and Velcade, respectively), and Demadex and Velcade (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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