Demerol and Integrilin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Demerol (meperidine hydrochloride) and Integrilin (eptifibatide). Common drug interactions include alanine aminotransferase decreased among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Demerol and Integrilin. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Demerol?

Demerol has active ingredients of meperidine hydrochloride. It is often used in pain. eHealthMe is studying from 12,706 Demerol users. Check the latest studies of Demerol.

What is Integrilin?

Integrilin has active ingredients of eptifibatide. eHealthMe is studying from 3,037 Integrilin users. Check the latest studies of Integrilin.

On Aug, 07, 2026

15 people who take Demerol and Integrilin together, and have interactions are studied.

Demerol and Integrilin drug interactions.

What are the common drug interactions of Demerol and Integrilin, by gender? *:

female:

Alanine aminotransferase decreased
Angina pectoris (chest pain due to ischemia of the heart muscle)
Apnoea (suspension of external breathing)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrioventricular block first degree (heart block first degree)
Blood bilirubin increased
Blood creatinine increased
Blood pressure decreased
Blood sodium increased
Blood thyroid stimulating hormone decreased

male:

Anaemia (lack of blood)
Arthralgia (joint pain)
Lymphoma (cancer that begins in immune system cells)
Anxiety
Back pain
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Death
Diarrhoea
Hypoglycaemia (deficiency of glucose in the bloodstream)

What are the common drug interactions of Demerol and Integrilin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cardiogenic shock (inadequate circulation of blood)
Injury
Psychiatric symptom
Renal failure (kidney dysfunction)

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Death
Emotional distress
Fear
Injury
Multi-organ failure (multisystem organ failure)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Renal injury (kidney injury)

50-59:

n/a

60+:

Injury
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Abdominal pain upper
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Acute myocardial infarction (acute heart attack)
Alanine aminotransferase decreased
Angina pectoris (chest pain due to ischemia of the heart muscle)
Apnoea (suspension of external breathing)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrioventricular block first degree (heart block first degree)

What are the existing conditions these people have? *

High Blood Pressure: 6 people, 40.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 33.33%
Stress And Anxiety: 4 people, 26.67%
Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 26.67%
Nausea (feeling of having an urge to vomit): 4 people, 26.67%
High Blood Cholesterol: 4 people, 26.67%
Agitation (state of anxiety or nervous excitement): 4 people, 26.67%
Osteoporosis (bones weak and more likely to break): 1 person, 6.67%
Myocardial Reperfusion Injury (tissue damage of heart muscle caused when blood supply returns to the tissue after a period of ischemia or lack of oxygen): 1 person, 6.67%
Hypokalemia (low potassium): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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