Demerol and Meridia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Demerol (meperidine hydrochloride) and Meridia (sibutramine hydrochloride). Common drug interactions include bronchitis among females.

The phase IV clinical study analyzes what interactions people have when they take Demerol and Meridia. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Demerol?

Demerol has active ingredients of meperidine hydrochloride. It is often used in pain. eHealthMe is studying from 12,706 Demerol users. Check the latest studies of Demerol.

What is Meridia?

Meridia has active ingredients of sibutramine hydrochloride. It is often used in weight loss. eHealthMe is studying from 6,939 Meridia users. Check the latest studies of Meridia.

On Jul, 05, 2026

19 people who take Demerol and Meridia together, and have interactions are studied.

What are the common drug interactions of Demerol and Meridia, by gender? *:

female:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Presyncope
Renal failure (kidney dysfunction)
Sinusitis (inflammation of sinus)
Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
Tuberculin test positive
Uterine cancer
Cardiomyopathy (weakening of the heart muscle)
Hypertension (high blood pressure)

male:

n/a

What are the common drug interactions of Demerol and Meridia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Pulmonary oedema (fluid accumulation in the lungs)
Vomiting
Pulmonary hypertension (increase in blood pressure in the lung artery)
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Device related infection
Endometrial cancer
Fatigue (feeling of tiredness)
Gangrene (body tissue dies)
Hyperlipidaemia (presence of excess lipids in the blood)
Urinary incontinence (inability to control the flow of urine and involuntary urination)

30-39:

Constipation
Dyspnoea exertional (breathlessness or shortness of breath)
Hypoaesthesia (reduced sense of touch or sensation)
Malaise (a feeling of general discomfort or uneasiness)
Restlessness (not able to rest)
Unexpected therapeutic effect

40-49:

Acidosis (build-up of carbon dioxide in the blood)
Coma (state of unconsciousness lasting more than six hours)
Arrhythmia supraventricular (irregular heartbeat supraventricular origin)
Asthenia (weakness)
Blood pressure increased
Blunted affect (lack of emotional reactivity)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Cogwheel rigidity (tension in a muscle which gives way in little jerks when the muscle is stretched)
Communication disorder (speech and language disorder)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Tremor (trembling or shaking movements in one or more parts of your body): 3 people, 15.79%
Thyroid Diseases: 3 people, 15.79%
Stress And Anxiety: 3 people, 15.79%
Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 15.79%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 3 people, 15.79%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 3 people, 15.79%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 15.79%
Hypersensitivity: 3 people, 15.79%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 3 people, 15.79%
Fat Intolerance (inability to use fat by digestive system): 3 people, 15.79%

* Approximation only. Some reports may have incomplete information.

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