Demerol and Nitrostat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Demerol (meperidine hydrochloride) and Nitrostat (nitroglycerin). Common drug interactions include cardiac failure congestive among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Demerol and Nitrostat. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Demerol?

Demerol has active ingredients of meperidine hydrochloride. It is often used in pain. eHealthMe is studying from 12,706 Demerol users. Check the latest studies of Demerol.

What is Nitrostat?

Nitrostat has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 14,082 Nitrostat users. Check the latest studies of Nitrostat.

On Jul, 12, 2026

55 people who take Demerol and Nitrostat together, and have interactions are studied.

Demerol and Nitrostat drug interactions.

What are the common drug interactions of Demerol and Nitrostat, by gender? *:

female:

Cardiac failure congestive
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cough
Cyst (a closed sac)
Fatigue (feeling of tiredness)
Hospitalisation
Hot flush (sudden feelings of heat)
Loss of consciousness
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Pulmonary embolism (blockage of the main artery of the lung)

male:

Asthenia (weakness)
Depression
Eye infection
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Respiratory depression (respiration has a rate below 12 breaths)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Anxiety
Confusional state
Dizziness
Hepatitis c

What are the common drug interactions of Demerol and Nitrostat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cardiac disorder
Type 1 diabetes mellitus
Cardiac failure congestive
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Joint injury
Prothrombin level increased
Thrombosis (formation of a blood clot inside a blood vessel)
Viral cardiomyopathy (weakness in the muscle of the heart due to viral infection)

30-39:

Asthenia (weakness)
Back pain
Blood cholesterol increased
Cogwheel rigidity (tension in a muscle which gives way in little jerks when the muscle is stretched)
Complex partial seizures (epileptic seizure)
Contusion (a type of hematoma of tissue in which capillaries)
Cough
Dysarthria (speech disorder)
Facial palsy (paralysis of face nerve)
Fall

40-49:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Dehydration (dryness resulting from the removal of water)
Depression
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Eye infection
Gastritis (inflammation of stomach)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Pneumonia
Respiratory depression (respiration has a rate below 12 breaths)

50-59:

Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Renal failure (kidney dysfunction)
Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)
Thrombosis (formation of a blood clot inside a blood vessel)
White blood cell count decreased
Drug hypersensitivity
Alopecia areata (patchy baldness that typically begins with rapid hair loss)
Alopecia totalis (loss of all head hair)
Amylase increased

60+:

Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Constipation
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Decreased appetite
Depression
Fall
Fluid retention (an abnormal accumulation of fluid in the blood)
Haematoma (collection of blood outside the blood vessels)
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 9.09%
Nausea (feeling of having an urge to vomit): 4 people, 7.27%
High Blood Cholesterol: 4 people, 7.27%
Type 2 Diabetes: 3 people, 5.45%
Stress And Anxiety: 3 people, 5.45%
Post-Traumatic Stress Disorder: 3 people, 5.45%
Insomnia (sleeplessness): 3 people, 5.45%
High Blood Pressure: 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

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