Depakote er and Azithromycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Depakote er (divalproex sodium) and Azithromycin (azithromycin). Common drug interactions include pleuritic pain among females and fibula fracture among males.

The phase IV clinical study analyzes what interactions people have when they take Depakote er and Azithromycin. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Depakote er?

Depakote er has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 6,042 Depakote er users. Check the latest studies of Depakote er.

What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.

On Jul, 08, 2026

20 people who take Depakote er and Azithromycin together, and have interactions are studied.

Depakote er and Azithromycin drug interactions.

What are the common drug interactions of Depakote Er and Azithromycin, by gender? *:

female:

Pleuritic pain
Productive cough
Pulmonary congestion (congestion in the lungs)
Pulmonary embolism (blockage of the main artery of the lung)
Radiculitis lumbosacral (inflammation of nerve root at labosacral vertebrea)
Pain
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Injury
Anxiety

male:

Fibula fracture
Tibia fracture (fracture of lower leg bone)
Osteoporosis (bones weak and more likely to break)
Pain
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Ankle fracture
Anxiety
Chronic kidney disease
Emotional distress

What are the common drug interactions of Depakote Er and Azithromycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Biliary colic
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Dyspepsia (indigestion)
Gallbladder disorder
Gallbladder injury

30-39:

Injury
Pain
Anxiety
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dyspnoea (difficult or laboured respiration)
Emotional distress
Fear
General physical health deterioration (weak health status)

40-49:

Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
Liver transplant
Anxiety
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Emotional distress
General physical health deterioration (weak health status)
Injury
Pain

50-59:

Fall
Foot fracture
Gastrointestinal infection (infection of stomach and intestine)
Liver disorder (liver diseases)
Lower limb fracture
Malaise (a feeling of general discomfort or uneasiness)
Myasthenia gravis crisis (a paralysis of the respiratory muscles occurs)
Pancreatic disorder
Respiration (transport of oxygen from the outside air to the cells within tissues)
Urinary tract infection

60+:

Asthenia (weakness)
Diarrhoea
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

What are the existing conditions these people have? *

Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 5 people, 25.00%
Acne (skin problems that cause pimples): 4 people, 20.00%
Birth Control: 3 people, 15.00%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 15.00%
Stress And Anxiety: 2 people, 10.00%
Menstruation Irregular: 2 people, 10.00%
Depression: 2 people, 10.00%
Hypoglobulinaemia (deficiency of globulin in the bloodstream): 2 people, 10.00%
Migraine (headache): 2 people, 10.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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