Depo-testosterone and Bactrim drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Depo-testosterone (testosterone cypionate) and Bactrim (sulfamethoxazole; trimethoprim). Common drug interactions include burning sensation among females and depression among males.

The phase IV clinical study analyzes what interactions people have when they take Depo-testosterone and Bactrim. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Depo-testosterone?

Depo-testosterone has active ingredients of testosterone cypionate. It is often used in low testosterone. eHealthMe is studying from 4,295 Depo-testosterone users. Check the latest studies of Depo-testosterone.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

On Jul, 09, 2026

35 people who take Depo-testosterone and Bactrim together, and have interactions are studied.

Depo-testosterone and Bactrim drug interactions.

What are the common drug interactions of Depo-Testosterone and Bactrim, by gender? *:

female:

Burning sensation
Drug ineffective
Erythema (redness of the skin)
Full blood count decreased
Injection site induration
Leukaemia (blood or bone marrow cancer)
Malaise (a feeling of general discomfort or uneasiness)

male:

Depression
Fatigue (feeling of tiredness)
Sleep disorder
Suicidal ideation
Pain
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Rash
Acquired immunodeficiency syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv))
Acute myocardial infarction (acute heart attack)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

What are the common drug interactions of Depo-Testosterone and Bactrim, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Burning sensation
Drug ineffective
Erythema (redness of the skin)
Injection site induration

30-39:

Anxiety
Depression
Fatigue (feeling of tiredness)
Sleep disorder
Acute myocardial infarction (acute heart attack)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Anaemia (lack of blood)
Cellulitis (infection under the skin)
Leukopenia (less number of white blood cells in blood)
Lumbar radiculopathy (radicular pain in the low back and legs)

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Chronic kidney disease
Emotional distress
Hip arthroplasty
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain

50-59:

Acquired immunodeficiency syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv))
Ascites (accumulation of fluid in the abdominal cavity)
Chronic kidney disease
Hepatitis c
Neuropathy peripheral (surface nerve damage)
Renal failure (kidney dysfunction)
Diplopia (double vision)
Headache (pain in head)
Meningitis viral (viral inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

60+:

Blood creatinine increased
Fatigue (feeling of tiredness)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cellulitis (infection under the skin)
Cough
Diarrhoea
Diarrhoea haemorrhagic (bloody diarrhoea)
Erectile dysfunction
Gastric infection (infection of stomach)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)

What are the existing conditions these people have? *

High Blood Pressure: 6 people, 17.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 17.14%
Hiv Infection: 4 people, 11.43%
Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 11.43%
Plantar Fasciitis (painful inflammatory process of the plantar fascia): 4 people, 11.43%
Depression: 4 people, 11.43%
Diabetes: 4 people, 11.43%
Joint Pain: 4 people, 11.43%
Headache (pain in head): 4 people, 11.43%
High Blood Cholesterol: 4 people, 11.43%

* Approximation only. Some reports may have incomplete information.

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