Desyrel and Acular drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Desyrel (trazodone hydrochloride) and Acular (ketorolac tromethamine). Common drug interactions include pain among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Desyrel and Acular. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Desyrel?

Desyrel has active ingredients of trazodone hydrochloride. It is often used in insomnia. eHealthMe is studying from 6,595 Desyrel users. Check the latest studies of Desyrel.

What is Acular?

Acular has active ingredients of ketorolac tromethamine. eHealthMe is studying from 1,125 Acular users. Check the latest studies of Acular.

On Jul, 11, 2026

14 people who take Desyrel and Acular together, and have interactions are studied.

What are the common drug interactions of Desyrel and Acular, by gender? *:

female:

Pain
Small intestinal obstruction (blockage in small intestine)
Actinic keratosis (skin disease due to sun exposure)
Cataract (clouding of the lens inside the eye)
Death
Gamma-glutamyltransferase increased
Hyperlipidaemia (presence of excess lipids in the blood)
Hypokalaemia (low potassium)
Trigger finger
Abdominal pain

male:

Drug ineffective
Dyspnoea (difficult or laboured respiration)
Gait disturbance
Muscle spasms (muscle contraction)
Overdose
Pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Gastric ulcer perforation (stomach hole due to ulcer)

What are the common drug interactions of Desyrel and Acular, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Gastric ulcer perforation (stomach hole due to ulcer)

60+:

Pain
Abdominal pain
Actinic keratosis (skin disease due to sun exposure)
Cataract (clouding of the lens inside the eye)
Death
Gamma-glutamyltransferase increased
Hyperlipidaemia (presence of excess lipids in the blood)
Hypokalaemia (low potassium)
Trigger finger
Drug ineffective

What are the existing conditions these people have? *

Pain: 11 people, 78.57%
Stress And Anxiety: 10 people, 71.43%
Sleep Disorder: 7 people, 50.00%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 5 people, 35.71%
Temperature Intolerance (inability to go in temperature): 5 people, 35.71%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 5 people, 35.71%
Mineral Deficiency (lack of mineral): 5 people, 35.71%
Muscle Aches (muscle pain): 5 people, 35.71%
Muscle Spasms (muscle contraction): 4 people, 28.57%
Abdominal Pain: 4 people, 28.57%

* Approximation only. Some reports may have incomplete information.

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