Desyrel and Colecalciferol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Desyrel (trazodone hydrochloride) and Colecalciferol (cholecalciferol). Common drug interactions include fatigue among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Desyrel and Colecalciferol. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Desyrel?

Desyrel has active ingredients of trazodone hydrochloride. It is often used in insomnia. eHealthMe is studying from 6,595 Desyrel users. Check the latest studies of Desyrel.

What is Colecalciferol?

Colecalciferol has active ingredients of cholecalciferol. eHealthMe is studying from 21,262 Colecalciferol users. Check the latest studies of Colecalciferol.



On Jul, 14, 2026

13 people who take Desyrel and Colecalciferol together, and have interactions are studied.

Desyrel and Colecalciferol drug interactions.

What are the common drug interactions of Desyrel and Colecalciferol, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Gait disturbance
  3. Nausea (feeling of having an urge to vomit)
  4. Pain
  5. Productive cough
  6. Somnolence (a state of near-sleep, a strong desire for sleep)
  7. Wheezing (a high-pitched whistling sound made while you breath)
  8. Abdominal pain lower
  9. Anxiety
  10. Arthralgia (joint pain)

male:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Emotional distress
  4. Foot fracture
  5. Osteopenia (a condition where bone mineral density is lower than normal)
  6. Pain

What are the common drug interactions of Desyrel and Colecalciferol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Anxiety
  2. Asthenia (weakness)
  3. Drug ineffective
  4. Dry mouth
  5. Dyspepsia (indigestion)
  6. Dyspnoea (difficult or laboured respiration)
  7. Fatigue (feeling of tiredness)
  8. Fibromyalgia (a long-term condition which causes pain all over the body)
  9. Gait disturbance
  10. Hypoaesthesia (reduced sense of touch or sensation)

50-59:

  1. Pain
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Anxiety
  4. Blood glucose increased
  5. Blood pressure increased
  6. Emotional distress
  7. Fall
  8. Fatigue (feeling of tiredness)
  9. Foot fracture
  10. Gait disturbance

60+:

  1. Abdominal pain lower
  2. Arthralgia (joint pain)
  3. Flatulence (flatus expelled through the anus)
  4. Hypopharyngeal cancer
  5. Lower respiratory tract infection
  6. Lung disorder (lung disease)
  7. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  8. Nasopharyngitis (inflammation of the nasopharynx)
  9. Nausea (feeling of having an urge to vomit)
  10. Oedema peripheral (superficial swelling)

What are the existing conditions these people have? *

  1. Pain: 3 people, 23.08%
  2. Dyspnea (difficult or laboured breathing): 3 people, 23.08%
  3. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 15.38%
  4. Migraine (headache): 2 people, 15.38%
  5. High Blood Cholesterol: 2 people, 15.38%
  6. Nausea (feeling of having an urge to vomit): 2 people, 15.38%
  7. Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 15.38%
  8. Wheezing (a high-pitched whistling sound made while you breath): 2 people, 15.38%
  9. Chest Pain: 2 people, 15.38%
  10. Sleep Disorder: 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

Do you take Desyrel and Colecalciferol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Desyrel and Colecalciferol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Desyrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Colecalciferol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Desyrel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Colecalciferol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on trazodone hydrochloride and cholecalciferol (the active ingredients of Desyrel and Colecalciferol, respectively), and Desyrel and Colecalciferol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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