Desyrel and Dostinex drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Desyrel (trazodone hydrochloride) and Dostinex (cabergoline). Common drug interactions include hunger among females and somnolence among males.
The phase IV clinical study analyzes what interactions people have when they take Desyrel and Dostinex. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Desyrel?
Desyrel has active ingredients of trazodone hydrochloride. It is often used in insomnia. eHealthMe is studying from 6,595 Desyrel users. Check the latest studies of Desyrel.
What is Dostinex?
Dostinex has active ingredients of cabergoline. It is often used in prolactinoma. eHealthMe is studying from 3,064 Dostinex users. Check the latest studies of Dostinex.
13 people who take Desyrel and Dostinex together, and have interactions are studied.

What are the common drug interactions of Desyrel and Dostinex, by gender? *:
female:
- Hunger
- Merycism (a rare disease in which food is chewed, swallowed, and then returned to the mouth and chewed again)
- Muscle spasms (muscle contraction)
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
- Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
- Periodic limb movement disorder
- Pseudodementia (severe form of depression that results from a progressive brain disorder in which cognitive changes mimic those of dementia)
- Sleep paralysis (waking up and unable to move or speak)
- Snoring
- Stress
male:
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Fall
- Fatigue (feeling of tiredness)
- Feeling cold
- Hypersomnia (excessive daytime sleepiness (eds))
- Hypoaesthesia (reduced sense of touch or sensation)
- Incontinence (lack of moderation or self-control)
- Lethargy (tiredness)
- Muscle spasms (muscle contraction)
What are the common drug interactions of Desyrel and Dostinex, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Syncope (loss of consciousness with an inability to maintain postural tone)
40-49:
- Memory impairment
- Mood altered (changes in mood)
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Snoring
- Weight increased
- Abnormal behaviour
- Adjustment disorder
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Blood testosterone decreased
- Breath sounds decreased
50-59:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Contusion (a type of hematoma of tissue in which capillaries)
- Crying
- Disturbance in attention
- Dyspnoea (difficult or laboured respiration)
- Dysuria (painful or difficult urination)
- Fatigue (feeling of tiredness)
- Heart rate increased
- Hunger
60+:
- Arthralgia (joint pain)
- Confusional state
- Fatigue (feeling of tiredness)
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Fibula fracture
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Polyarthritis (arthritis which involves 5 or more joints simultaneously)
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Fear
- Pneumonia
What are the existing conditions these people have? *
- Pain: 8 people, 61.54%
- Nausea (feeling of having an urge to vomit): 3 people, 23.08%
- Stress And Anxiety: 2 people, 15.38%
- Sleep Disorder: 2 people, 15.38%
- Liver Injury: 2 people, 15.38%
- Hypertriglyceridaemia (excess of triglycerides in the blood): 2 people, 15.38%
- High Blood Cholesterol: 2 people, 15.38%
- Glaucoma (increased fluid pressure in the eye with vision loss): 2 people, 15.38%
- Depression: 2 people, 15.38%
- Constipation: 2 people, 15.38%
* Approximation only. Some reports may have incomplete information.
Do you take Desyrel and Dostinex?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Desyrel and Dostinex:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Desyrel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Dostinex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Desyrel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dostinex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Gürbüz F, Ya?c?-Küpeli B, K?r Y, Yüksel B, Zorludemir S, Gürbüz BB, Küpeli S, "The first report of cabergoline-induced immune hemolytic anemia in an adolescent with prolactinoma", Journal of Pediatric Endocrinology and Metabolism, 2014 Jan .
- Harris YT, Harris AZ, "Cabergoline associated with first episode mania", Psychosomatics, 2012 Jan .
- Gürbüz F, Ya?c?-Küpeli B, K?r Y, Yüksel B, Zorludemir S, Gürbüz BB, Küpeli S, "The first report of cabergoline-induced immune hemolytic anemia in an adolescent with prolactinoma", Journal of Pediatric Endocrinology and Metabolism, 2014 Jan .
- Harris YT, Harris AZ, "Cabergoline associated with first episode mania", Psychosomatics, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on trazodone hydrochloride and cabergoline (the active ingredients of Desyrel and Dostinex, respectively), and Desyrel and Dostinex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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