Desyrel and Sucralfate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Desyrel (trazodone hydrochloride) and Sucralfate (sucralfate). Common drug interactions include chronic kidney disease among females and large intestine perforation among males.

The phase IV clinical study analyzes what interactions people have when they take Desyrel and Sucralfate. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Desyrel?

Desyrel has active ingredients of trazodone hydrochloride. It is often used in insomnia. eHealthMe is studying from 6,595 Desyrel users. Check the latest studies of Desyrel.

What is Sucralfate?

Sucralfate has active ingredients of sucralfate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 17,548 Sucralfate users. Check the latest studies of Sucralfate.

On Jul, 06, 2026

21 people who take Desyrel and Sucralfate together, and have interactions are studied.

Desyrel and Sucralfate drug interactions.

What are the common drug interactions of Desyrel and Sucralfate, by gender? *:

female:

Chronic kidney disease
Impaired gastric emptying
Intestinal obstruction
Nausea (feeling of having an urge to vomit)
Renal failure (kidney dysfunction)
Abdominal distension
Abdominal pain
Abdominal pain upper
Anal abscess
Constipation

male:

Large intestine perforation (hole in large intestine)
Duodenal ulcer haemorrhage (bleeding duodenal ulcer)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haemorrhage (bleeding)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Normal pressure hydrocephalus (a neurological disorder in which there is too much cerebrospinal fluid in the ventricles of the brain)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Post procedural complication
Somnolence (a state of near-sleep, a strong desire for sleep)
Anaemia (lack of blood)

What are the common drug interactions of Desyrel and Sucralfate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood cholesterol increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Glaucoma (increased fluid pressure in the eye with vision loss)
Hypertension (high blood pressure)
Neuropathy peripheral (surface nerve damage)
Purpura senile (skin condition in which areas of the skin develop a purplish or reddish-brown appearance due to bleeding of small blood vessels underneath)
Renal failure (kidney dysfunction)
Resorption bone increased

40-49:

Nausea (feeling of having an urge to vomit)
Abdominal distension
Abdominal pain
Abdominal pain upper
Anal abscess
Constipation
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Drug ineffective
Drug level decreased
Dyspepsia (indigestion)

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)

60+:

Large intestine perforation (hole in large intestine)
Chronic kidney disease
Delirium (wild excitement)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haemorrhage (bleeding)
Nephrogenic anaemia (anaemia due to kidney disease)
Nephropathy (damage to or disease of a kidney)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Normal pressure hydrocephalus (a neurological disorder in which there is too much cerebrospinal fluid in the ventricles of the brain)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)

What are the existing conditions these people have? *

Pain: 9 people, 42.86%
High Blood Cholesterol: 7 people, 33.33%
High Blood Pressure: 7 people, 33.33%
Infection: 6 people, 28.57%
Stress And Anxiety: 5 people, 23.81%
Iron Deficiency Anaemia: 4 people, 19.05%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 19.05%
Gastric Ulcer (stomach ulcer): 4 people, 19.05%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 4 people, 19.05%
Folate Deficiency (lack of folic acid): 4 people, 19.05%

* Approximation only. Some reports may have incomplete information.

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