Detrol la and Flagyl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Detrol la (tolterodine tartrate) and Flagyl (metronidazole). Common drug interactions include multiple sclerosis relapse among females and dehydration among males.

The phase IV clinical study analyzes what interactions people have when they take Detrol la and Flagyl. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Detrol la?

Detrol la has active ingredients of tolterodine tartrate. It is often used in urge incontinence. eHealthMe is studying from 13,358 Detrol la users. Check the latest studies of Detrol la.

What is Flagyl?

Flagyl has active ingredients of metronidazole. It is often used in vaginitis bacterial. eHealthMe is studying from 25,897 Flagyl users. Check the latest studies of Flagyl.



On Aug, 04, 2026

23 people who take Detrol la and Flagyl together, and have interactions are studied.

Detrol la and Flagyl drug interactions.

What are the common drug interactions of Detrol La and Flagyl, by gender? *:

female:

  1. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Nephrogenic anaemia (anaemia due to kidney disease)
  4. Oesophageal discomfort (pain or burning feeling behind breast bone)
  5. Oesophageal pain
  6. Oesophageal ulcer (ulcer of oesophagus)
  7. Oesophagitis (inflammation of oesophagus)
  8. Opportunistic infection (a microorganism that normally does not cause disease but becomes pathogenic when the body's immune system is impaired and unable to fight)
  9. Oral pain
  10. Paraparesis (partial paralysis of the lower limbs)

male:

  1. Dehydration (dryness resulting from the removal of water)
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Blood bilirubin increased
  4. Blood urea increased
  5. C-reactive protein increased
  6. Candidiasis (candidiasis or thrush is a fungal infection)
  7. Cytomegalovirus viraemia (cytomegalo virus in blood stream)
  8. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  9. Dyspnoea (difficult or laboured respiration)
  10. Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)

What are the common drug interactions of Detrol La and Flagyl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Deafness unilateral
  2. Dyspepsia (indigestion)
  3. Dysphagia (a condition in which swallowing is difficult or painful)
  4. Haematemesis (vomiting of blood)
  5. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
  6. Hyperchlorhydria (gastric acid levels are higher in stomach)
  7. Hypersensitivity
  8. Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
  9. Impaired gastric emptying
  10. Injury

40-49:

  1. Affective disorder (mental disorder)
  2. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

50-59:

  1. Anxiety
  2. Asphyxia (a condition in which there is an extreme decrease in the concentration of oxygen in the body)
  3. Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
  4. Osteomyelitis (infection of bone)
  5. Urinary tract infection
  6. Blood glucose increased
  7. Pancreatitis acute (sudden inflammation of pancreas)
  8. Unresponsive to stimuli
  9. Asthenia (weakness)
  10. Bloody discharge

60+:

  1. Dehydration (dryness resulting from the removal of water)
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Blood bilirubin increased
  4. Blood urea increased
  5. Bruxism (habitual grinding of the teeth, typically during sleep)
  6. C-reactive protein increased
  7. Candidiasis (candidiasis or thrush is a fungal infection)
  8. Constipation
  9. Cytomegalovirus viraemia (cytomegalo virus in blood stream)
  10. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 17.39%
  2. Stress And Anxiety: 3 people, 13.04%
  3. Multiple Myeloma (cancer of the plasma cells): 3 people, 13.04%
  4. Type 2 Diabetes: 2 people, 8.70%
  5. Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 2 people, 8.70%
  6. High Blood Pressure: 2 people, 8.70%
  7. High Blood Cholesterol: 2 people, 8.70%
  8. Depression: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Detrol la and Flagyl?

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- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Detrol la and Flagyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Detrol la:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Flagyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Detrol la and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flagyl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tolterodine tartrate and metronidazole (the active ingredients of Detrol la and Flagyl, respectively), and Detrol la and Flagyl (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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