Detrol and Cytoxan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Detrol (tolterodine tartrate) and Cytoxan (cyclophosphamide). Common drug interactions include alopecia among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Detrol and Cytoxan. It is created by eHealthMe based on reports of 82 people who take the same drugs from the FDA, and is updated regularly.

What is Detrol?

Detrol has active ingredients of tolterodine tartrate. It is often used in urge incontinence. eHealthMe is studying from 28,669 Detrol users. Check the latest studies of Detrol.

What is Cytoxan?

Cytoxan has active ingredients of cyclophosphamide. It is often used in breast cancer. eHealthMe is studying from 19,693 Cytoxan users. Check the latest studies of Cytoxan.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 30, 2026

82 people who take Detrol and Cytoxan together, and have interactions are studied.

Detrol and Cytoxan drug interactions.

What are the common drug interactions of Detrol and Cytoxan, by gender? *:

female:

  1. Alopecia (absence of hair from areas of the body)
  2. Osteomyelitis (infection of bone)
  3. Osteonecrosis of jaw (death of bone of jaw)
  4. Haematuria (presence of blood in urine)
  5. Fall
  6. Osteoporosis (bones weak and more likely to break)
  7. Anaemia (lack of blood)
  8. Dyspnoea (difficult or laboured respiration)
  9. Nausea (feeling of having an urge to vomit)
  10. Pleural effusion (water on the lungs)

male:

  1. Anaemia (lack of blood)
  2. Chest pain
  3. Arteriosclerosis (thickening and hardening of arteries)
  4. Asthenia (weakness)
  5. Asthma
  6. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  7. Cardiac murmur (an heart sound in valve abnormality)
  8. Cardiomegaly (increased size of heart than normal)
  9. Cataract (clouding of the lens inside the eye)
  10. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the common drug interactions of Detrol and Cytoxan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Anaemia (lack of blood)
  2. Anxiety
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Dyspnoea exertional (breathlessness or shortness of breath)
  6. Fall
  7. Haematuria (presence of blood in urine)
  8. Osteomyelitis (infection of bone)
  9. Osteonecrosis of jaw (death of bone of jaw)
  10. Osteoporosis (bones weak and more likely to break)

20-29:

n/a

30-39:

n/a

40-49:

  1. Drug ineffective

50-59:

  1. Dyspnoea (difficult or laboured respiration)
  2. Injury
  3. Nausea (feeling of having an urge to vomit)
  4. Osteomyelitis (infection of bone)
  5. Ovarian cancer metastatic (cancer of ovary spreads to other organ or parts)
  6. Pleural effusion (water on the lungs)
  7. Sinus disorder (disease of sinus)
  8. Swelling
  9. Osteonecrosis of jaw (death of bone of jaw)
  10. Toothache (tooth pain)

60+:

  1. Fall
  2. Loose tooth
  3. Fatigue (feeling of tiredness)
  4. Pulmonary embolism (blockage of the main artery of the lung)
  5. Asthenia (weakness)
  6. Decreased appetite
  7. Bone disorder
  8. Chest pain
  9. Dyspnoea (difficult or laboured respiration)
  10. Hyperkeratosis (thickening of the outer layer of the skin)

What are the existing conditions these people have? *

  1. Breast Cancer Female: 17 people, 20.73%
  2. Herpes Virus Infection: 13 people, 15.85%
  3. Nausea (feeling of having an urge to vomit): 12 people, 14.63%
  4. Insomnia (sleeplessness): 11 people, 13.41%
  5. Ovarian Cancer (cancer of ovary): 10 people, 12.20%
  6. Muscle Aches (muscle pain): 10 people, 12.20%
  7. Osteoporosis (bones weak and more likely to break): 6 people, 7.32%

* Approximation only. Some reports may have incomplete information.

Do you take Detrol and Cytoxan?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Detrol and Cytoxan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Detrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cytoxan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Detrol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cytoxan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on tolterodine tartrate and cyclophosphamide (the active ingredients of Detrol and Cytoxan, respectively), and Detrol and Cytoxan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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