Detrol and Estropipate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Detrol (tolterodine tartrate) and Estropipate (estropipate). Common drug interactions include dizziness among females and memory impairment among males.

The phase IV clinical study analyzes what interactions people have when they take Detrol and Estropipate. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Detrol?

Detrol has active ingredients of tolterodine tartrate. It is often used in urge incontinence. eHealthMe is studying from 28,669 Detrol users. Check the latest studies of Detrol.

What is Estropipate?

Estropipate has active ingredients of estropipate. It is often used in hormone replacement therapy. eHealthMe is studying from 1,659 Estropipate users. Check the latest studies of Estropipate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 14, 2026

17 people who take Detrol and Estropipate together, and have interactions are studied.

Detrol and Estropipate drug interactions.

What are the common drug interactions of Detrol and Estropipate, by gender? *:

female:

Dizziness
Blood pressure fluctuation
Colon neoplasm (cancer from uncontrolled cell growth in the colon or rectum)
Dehydration (dryness resulting from the removal of water)
Nocturia (the need to get up in the night to urinate)
Retching (strong involuntary effort to vomit)
Vomiting
Anaemia of chronic disease
Aortic valve disease
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)

male:

Memory impairment
Micturition urgency (urgency to pass the urine)
Multiple fractures
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

What are the common drug interactions of Detrol and Estropipate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood triglycerides increased
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Diarrhoea
Dry mouth
Flushing (the warm, red condition of human skin)
Gallbladder operation
Generalised erythema (redness of the skin all over the body)
High density lipoprotein decreased

60+:

Dry mouth
Fatigue (feeling of tiredness)
Retching (strong involuntary effort to vomit)
Vomiting
Anaemia of chronic disease
Aortic valve disease
Back disorder
Cardiac failure congestive
Cellulitis (infection under the skin)
Cough

What are the existing conditions these people have? *

Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 3 people, 17.65%
Temporomandibular Joint Syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress): 2 people, 11.76%
Micturition Urgency (urgency to pass the urine): 2 people, 11.76%
Incontinence (lack of moderation or self-control): 2 people, 11.76%
Stress And Anxiety: 2 people, 11.76%
Feeling Of Relaxation: 1 person, 5.88%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 5.88%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.88%
Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 1 person, 5.88%
Insomnia (sleeplessness): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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