Detrol and Lialda drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Detrol (tolterodine tartrate) and Lialda (mesalamine). Common drug interactions include injection site bruising among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Detrol and Lialda. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Detrol?

Detrol has active ingredients of tolterodine tartrate. It is often used in urge incontinence. eHealthMe is studying from 28,669 Detrol users. Check the latest studies of Detrol.

What is Lialda?

Lialda has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 10,199 Lialda users. Check the latest studies of Lialda.



On Jul, 22, 2026

11 people who take Detrol and Lialda together, and have interactions are studied.

Detrol and Lialda drug interactions.

What are the common drug interactions of Detrol and Lialda, by gender? *:

female:

  1. Injection site bruising
  2. Constipation
  3. Drug administration error
  4. Faecaloma (hard mass of fecal matter)
  5. Headache (pain in head)
  6. Injection site erythema (redness at injection site)
  7. Injection site pain
  8. Injection site papule (solid pimple or swelling at injection site)
  9. Injection site pruritus (severe itching at injection site)
  10. Injection site urticaria (rash of round, red welts on the skin at injection site)

male:

  1. Abdominal distension
  2. Asthenia (weakness)
  3. Ocular hyperaemia (an abnormally large amount of blood in eye)
  4. Platelet count decreased
  5. Post procedural complication
  6. Pyrexia (fever)
  7. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  8. Somnolence (a state of near-sleep, a strong desire for sleep)
  9. Brain neoplasm (tumour of brain)
  10. Cataract (clouding of the lens inside the eye)

What are the common drug interactions of Detrol and Lialda, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Injection site bruising
  2. Injection site erythema (redness at injection site)
  3. Injection site papule (solid pimple or swelling at injection site)
  4. Injection site pruritus (severe itching at injection site)

40-49:

  1. Injection site pain
  2. Injection site urticaria (rash of round, red welts on the skin at injection site)

50-59:

n/a

60+:

  1. Headache (pain in head)
  2. Abdominal distension
  3. Feeding disorder (when children refuse to eat certain food groups)
  4. Hypersomnia (excessive daytime sleepiness (eds))
  5. Hypertension (high blood pressure)
  6. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  7. Ocular hyperaemia (an abnormally large amount of blood in eye)
  8. Platelet count decreased
  9. Post procedural complication
  10. Pyrexia (fever)

What are the existing conditions these people have? *

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 45.45%
  2. Thyroid Diseases: 2 people, 18.18%
  3. Impaired Gastric Emptying: 2 people, 18.18%
  4. Bladder Disorder: 2 people, 18.18%
  5. Cystitis Interstitial (unknown cause characterized by bladder pain): 2 people, 18.18%
  6. Depression: 2 people, 18.18%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 18.18%
  8. Stress And Anxiety: 2 people, 18.18%
  9. Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 2 people, 18.18%
  10. Laxative Supportive Care: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Detrol and Lialda?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Detrol and Lialda:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Detrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lialda:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Detrol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lialda and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on tolterodine tartrate and mesalamine (the active ingredients of Detrol and Lialda, respectively), and Detrol and Lialda (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: