Detrol and Maxalt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Detrol (tolterodine tartrate) and Maxalt (rizatriptan benzoate). Common drug interactions include pancreatic pseudocyst among females and agitation among males.

The phase IV clinical study analyzes what interactions people have when they take Detrol and Maxalt. It is created by eHealthMe based on reports of 81 people who take the same drugs from the FDA, and is updated regularly.

What is Detrol?

Detrol has active ingredients of tolterodine tartrate. It is often used in urge incontinence. eHealthMe is studying from 28,669 Detrol users. Check the latest studies of Detrol.

What is Maxalt?

Maxalt has active ingredients of rizatriptan benzoate. It is often used in migraine. eHealthMe is studying from 12,754 Maxalt users. Check the latest studies of Maxalt.



On Jul, 08, 2026

81 people who take Detrol and Maxalt together, and have interactions are studied.

Detrol and Maxalt drug interactions.

What are the common drug interactions of Detrol and Maxalt, by gender? *:

female:

  1. Pancreatic pseudocyst (collection of tissue and fluids that forms on pancreas)
  2. Pancreatitis (inflammation of pancreas)
  3. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  4. Pneumonia
  5. Pulmonary embolism (blockage of the main artery of the lung)
  6. Sneezing
  7. Somnolence (a state of near-sleep, a strong desire for sleep)
  8. Stress
  9. Tooth disorder (tooth disease)
  10. Fall

male:

  1. Agitation (state of anxiety or nervous excitement)
  2. Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
  3. Pain
  4. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  5. Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
  6. Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
  7. Psychotic disorder
  8. Respiratory failure (inadequate gas exchange by the respiratory system)
  9. Stress
  10. Surgery

What are the common drug interactions of Detrol and Maxalt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal pain
  2. Acidosis (build-up of carbon dioxide in the blood)
  3. Cardiac arrest
  4. Cholecystitis (infection of gallbladder)
  5. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  6. Death
  7. Fluid overload (too much fluid in the blood)
  8. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  9. Hypertension (high blood pressure)
  10. Hypotension (abnormally low blood pressure)

40-49:

  1. Anxiety
  2. Back disorder
  3. Depression
  4. Fall
  5. Fatigue (feeling of tiredness)
  6. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  7. Panic attack
  8. Road traffic accident
  9. Vomiting
  10. Bedridden

50-59:

  1. Pain in jaw
  2. Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
  3. Renal failure (kidney dysfunction)
  4. Tooth disorder (tooth disease)
  5. Fall
  6. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  7. Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
  8. Urinary tract infection
  9. Bladder dysfunction
  10. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)

60+:

  1. Urinary tract infection
  2. Chronic kidney disease
  3. Agitation (state of anxiety or nervous excitement)
  4. Arthritis bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection)
  5. Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
  6. Bile duct stone
  7. Bipolar disorder (mood disorder)
  8. Bladder dysfunction
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  10. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the existing conditions these people have? *

  1. Pain: 24 people, 29.63%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 20 people, 24.69%
  3. Fibromyalgia (a long-term condition which causes pain all over the body): 17 people, 20.99%
  4. Depression: 17 people, 20.99%
  5. Stress And Anxiety: 13 people, 16.05%
  6. Sleep Disorder: 11 people, 13.58%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 12.35%
  8. Cystitis Interstitial (unknown cause characterized by bladder pain): 9 people, 11.11%
  9. Restless Leg Syndrome (a powerful urge to move your legs): 8 people, 9.88%
  10. Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 8 people, 9.88%

* Approximation only. Some reports may have incomplete information.

Do you take Detrol and Maxalt?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Detrol and Maxalt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Detrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Maxalt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Detrol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Maxalt and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tolterodine tartrate and rizatriptan benzoate (the active ingredients of Detrol and Maxalt, respectively), and Detrol and Maxalt (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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