Dexacort and Zofran drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dexacort (dexamethasone sodium phosphate) and Zofran (ondansetron hydrochloride). Common drug interactions include febrile neutropenia among females and duodenal ulcer haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Dexacort and Zofran. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Dexacort?

Dexacort has active ingredients of dexamethasone sodium phosphate. eHealthMe is studying from 138 Dexacort users. Check the latest studies of Dexacort.

What is Zofran?

Zofran has active ingredients of ondansetron hydrochloride. It is often used in nausea. eHealthMe is studying from 94,987 Zofran users. Check the latest studies of Zofran.

On Jul, 14, 2026

15 people who take Dexacort and Zofran together, and have interactions are studied.

What are the common drug interactions of Dexacort and Zofran, by gender? *:

female:

Febrile neutropenia (fever with reduced white blood cells)
Klebsiella infection
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Dyspnoea (difficult or laboured respiration)
Oedema peripheral (superficial swelling)
Pulmonary embolism (blockage of the main artery of the lung)
Pyrexia (fever)
Hepatic enzyme increased
Sepsis (a severe blood infection that can lead to organ failure and death)
Bacteraemia (presence of bacteria in the blood)

male:

Duodenal ulcer haemorrhage (bleeding duodenal ulcer)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Staphylococcal infection (an infection with staphylococcus bacteria)
Thrombosis (formation of a blood clot inside a blood vessel)
Pyrexia (fever)
Arrhythmia (irregular heartbeat)
General physical health deterioration (weak health status)
Infection
Palpitations (feelings or sensations that your heart is pounding or racing)
Procedural site reaction

What are the common drug interactions of Dexacort and Zofran, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Dyspnoea (difficult or laboured respiration)
Oedema peripheral (superficial swelling)
Pulmonary embolism (blockage of the main artery of the lung)
Pyrexia (fever)

50-59:

Palpitations (feelings or sensations that your heart is pounding or racing)
Arrhythmia (irregular heartbeat)
Chest pressure sensation (feeling of pressure on chest)
Infection
Procedural site reaction
Pulsus bigeminus (groups of two heartbeats close together followed by a longer pause)
Pyrexia (fever)
Sepsis (a severe blood infection that can lead to organ failure and death)
Staphylococcal infection (an infection with staphylococcus bacteria)
Thrombosis (formation of a blood clot inside a blood vessel)

60+:

Duodenal ulcer haemorrhage (bleeding duodenal ulcer)
Febrile neutropenia (fever with reduced white blood cells)
Laboratory test abnormal
Platelet count decreased
Pyrexia (fever)
Klebsiella infection
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Hepatic enzyme increased
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the existing conditions these people have? *

Pain: 5 people, 33.33%
Lung Cancer - Non-Small Cell (lung cancer): 4 people, 26.67%
Diarrhea: 3 people, 20.00%
Nausea And Vomiting: 3 people, 20.00%
Anaemia (lack of blood): 3 people, 20.00%
Kidney Stones: 3 people, 20.00%
Blood Creatinine Increased: 3 people, 20.00%
Indigestion: 3 people, 20.00%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 20.00%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 20.00%

* Approximation only. Some reports may have incomplete information.

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