Dexedrine and Detrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dexedrine (dextroamphetamine sulfate) and Detrol (tolterodine tartrate). Common drug interactions include hypertonic bladder among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Dexedrine and Detrol. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Dexedrine?

Dexedrine has active ingredients of dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 4,735 Dexedrine users. Check the latest studies of Dexedrine.

What is Detrol?

Detrol has active ingredients of tolterodine tartrate. It is often used in urge incontinence. eHealthMe is studying from 28,669 Detrol users. Check the latest studies of Detrol.

On Jul, 10, 2026

16 people who take Dexedrine and Detrol together, and have interactions are studied.

What are the common drug interactions of Dexedrine and Detrol, by gender? *:

female:

Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
Tremor (trembling or shaking movements in one or more parts of your body)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Arthralgia (joint pain)
Arthropathy
Chronic left ventricular failure (long lasting functional impairment of left ventricle of heart)
Dry eye (lack of adequate tears)
Drug ineffective
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Arthritis (form of joint disorder that involves inflammation of one or more joints)

male:

Pain
Stress
Surgery
Tendon injury

What are the common drug interactions of Dexedrine and Detrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Arthralgia (joint pain)
Arthropathy
Anxiety
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Hypersensitivity
Hypertension (high blood pressure)
Migraine (headache)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Vertigo
Weight decreased

60+:

Anxiety
Drug ineffective
Hot flush (sudden feelings of heat)
Hypertension (high blood pressure)
Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
Migraine (headache)
Renal disorder (kidney disease)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Tremor (trembling or shaking movements in one or more parts of your body)
Weight decreased

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 43.75%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 25.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 25.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 25.00%
Stress And Anxiety: 3 people, 18.75%
Migraine (headache): 3 people, 18.75%
High Blood Pressure: 3 people, 18.75%
Drowsiness: 3 people, 18.75%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 6.25%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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