Dexlansoprazole and Digoxin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Dexlansoprazole (dexlansoprazole) and Digoxin (digoxin). Common drug interactions include device failure among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Dexlansoprazole and Digoxin. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.
What is Dexlansoprazole?
Dexlansoprazole has active ingredients of dexlansoprazole. eHealthMe is studying from 3,192 Dexlansoprazole users. Check the latest studies of Dexlansoprazole.
What is Digoxin?
Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.
25 people who take Dexlansoprazole and Digoxin together, and have interactions are studied.

What are the common drug interactions of Dexlansoprazole and Digoxin, by gender? *:
female:
- Device failure
- Dyspnoea (difficult or laboured respiration)
- Asthenia (weakness)
- Dizziness
- Cardiac failure congestive
- Fatigue (feeling of tiredness)
- Hypotension (abnormally low blood pressure)
- Oxygen saturation decreased
- Sluggishness (lacking alertness)
- Infusion site bruising
male:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Dizziness
- Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
- Fatigue (feeling of tiredness)
- Haematochezia (passage of stools containing blood)
- Haemorrhage intracranial (bleeding within the skull)
- Hip fracture
- Hospitalisation
- Idiopathic thrombocytopenic purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting)
What are the common drug interactions of Dexlansoprazole and Digoxin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Renal impairment (severely reduced kidney function)
50-59:
- Dizziness
- Asthenia (weakness)
- Fatigue (feeling of tiredness)
- Hypotension (abnormally low blood pressure)
- Malaise (a feeling of general discomfort or uneasiness)
- Oxygen saturation decreased
- Sluggishness (lacking alertness)
- Chest pain
- Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
- Dry mouth
60+:
- Anaemia (lack of blood)
- Asthenia (weakness)
- Fatigue (feeling of tiredness)
- Fluid overload (too much fluid in the blood)
- Haematochezia (passage of stools containing blood)
- Haemoglobin decreased
- Haemorrhage intracranial (bleeding within the skull)
- Headache (pain in head)
- Hearing impaired
- Hip fracture
What are the existing conditions these people have? *
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 8 people, 32.00%
- Cardiac Failure: 5 people, 20.00%
- Diabetes: 4 people, 16.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 16.00%
- Depression: 3 people, 12.00%
- Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 8.00%
- Gout (uric acid crystals building up in the body): 2 people, 8.00%
- Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 8.00%
- Dyspnea (difficult or laboured breathing): 2 people, 8.00%
- High Blood Cholesterol: 2 people, 8.00%
* Approximation only. Some reports may have incomplete information.
Do you take Dexlansoprazole and Digoxin?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Dexlansoprazole (3,192 reports)
- Digoxin (93,740 reports)
Browse all drug interactions of Dexlansoprazole and Digoxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Dexlansoprazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Digoxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dexlansoprazole and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Digoxin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on dexlansoprazole and digoxin (the active ingredients of Dexlansoprazole and Digoxin, respectively), and Dexlansoprazole and Digoxin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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