Dexlansoprazole and Effexor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dexlansoprazole (dexlansoprazole) and Effexor (venlafaxine hydrochloride). Common drug interactions include pain among females and decreased appetite among males.

The phase IV clinical study analyzes what interactions people have when they take Dexlansoprazole and Effexor. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Dexlansoprazole?

Dexlansoprazole has active ingredients of dexlansoprazole. eHealthMe is studying from 3,192 Dexlansoprazole users. Check the latest studies of Dexlansoprazole.

What is Effexor?

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 99,493 Effexor users. Check the latest studies of Effexor.



On Jul, 11, 2026

32 people who take Dexlansoprazole and Effexor together, and have interactions are studied.

Dexlansoprazole and Effexor drug interactions.

What are the common drug interactions of Dexlansoprazole and Effexor, by gender? *:

female:

  1. Pain
  2. Peritoneal abscess
  3. Spinal fusion surgery
  4. Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
  5. Thrombocytopenia (decrease of platelets in blood)
  6. Upper respiratory tract infection
  7. Chronic kidney disease
  8. Hyperhidrosis (abnormally increased sweating)
  9. Anaemia (lack of blood)
  10. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)

male:

  1. Decreased appetite
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Diarrhoea
  4. Dyspnoea (difficult or laboured respiration)
  5. Fall
  6. Femur fracture
  7. Fluid retention (an abnormal accumulation of fluid in the blood)
  8. Haemorrhage (bleeding)
  9. Head and neck cancer
  10. Hypertension (high blood pressure)

What are the common drug interactions of Dexlansoprazole and Effexor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Diarrhoea
  2. Heart valve replacement
  3. Hospitalisation
  4. Hyperhidrosis (abnormally increased sweating)
  5. Abdominal pain upper
  6. Accidental exposure

40-49:

  1. Lymphocyte count decreased
  2. Activated partial thromboplastin time prolonged
  3. Alanine aminotransferase increased
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  5. Aspartate aminotransferase increased
  6. Blood creatinine decreased
  7. Blood glucose increased
  8. Cellulitis (infection under the skin)
  9. Drug eruption (adverse drug reaction of the skin)
  10. Eczema eyelids (patches of skin become rough and inflamed, with itching and bleeding blisters on eyelid)

50-59:

  1. Chronic kidney disease
  2. Anaemia (lack of blood)
  3. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  4. Duodenal ulcer
  5. Fear of disease
  6. Gallbladder disorder
  7. Gastric ulcer (stomach ulcer)
  8. Iron deficiency
  9. Irritable bowel syndrome
  10. Mania (a state of abnormally elevated or irritable mood)

60+:

  1. Dizziness
  2. Diarrhoea
  3. Burning sensation
  4. Injection site bruising
  5. Medial tibial stress syndrome (pain in medial part of tibia)
  6. Pain in extremity
  7. Renal cancer recurrent (cancer of kidney repeat)
  8. Vitamin d decreased
  9. Acute respiratory failure
  10. Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)

What are the existing conditions these people have? *

  1. Blood Pressure Abnormal: 6 people, 18.75%
  2. Fibromyalgia (a long-term condition which causes pain all over the body): 6 people, 18.75%
  3. High Blood Cholesterol: 6 people, 18.75%
  4. Irritable Bowel Syndrome: 6 people, 18.75%
  5. Pain: 5 people, 15.62%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 15.62%
  7. High Blood Pressure: 5 people, 15.62%
  8. Weight Decreased: 4 people, 12.50%
  9. Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 12.50%
  10. Autoimmune Disorder (a condition in which the immune system attacks the body's normal substances and tissue): 4 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Dexlansoprazole and Effexor?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Dexlansoprazole and Effexor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dexlansoprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Effexor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dexlansoprazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Effexor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on dexlansoprazole and venlafaxine hydrochloride (the active ingredients of Dexlansoprazole and Effexor, respectively), and Dexlansoprazole and Effexor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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