Dexrazoxane and Cefazolin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dexrazoxane (dexrazoxane hydrochloride) and Cefazolin (cefazolin sodium). Common drug interactions include aplastic anaemia among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Dexrazoxane and Cefazolin. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Dexrazoxane?

Dexrazoxane has active ingredients of dexrazoxane hydrochloride. eHealthMe is studying from 1,141 Dexrazoxane users. Check the latest studies of Dexrazoxane.

What is Cefazolin?

Cefazolin has active ingredients of cefazolin sodium. It is often used in infection. eHealthMe is studying from 15,157 Cefazolin users. Check the latest studies of Cefazolin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

25 people who take Dexrazoxane and Cefazolin together, and have interactions are studied.

Dexrazoxane and Cefazolin drug interactions.

What are the common drug interactions of Dexrazoxane and Cefazolin, by gender? *:

female:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Acute febrile neutrophilic dermatosis (skin disease characterized by the sudden onset of fever, leukocytosis, and tender)
Nausea (feeling of having an urge to vomit)
Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
Pancreatitis acute (sudden inflammation of pancreas)
Vomiting
Abscess (pus)
Acute lymphocytic leukaemia (cancer of the white blood cells)
Areflexia (absence of a reflex)
Arthralgia (joint pain)

male:

Arthralgia (joint pain)
Back pain
Bacterial infection
Blood pressure increased
Cellulitis (infection under the skin)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Epistaxis (bleed from the nose)
Fungal infection
Haematemesis (vomiting of blood)

What are the common drug interactions of Dexrazoxane and Cefazolin, by age (0-1 to 60+)? *:

0-1:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)

2-9:

Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Fungal infection
Lymphopenia (an abnormally low level of lymphocytes in the blood)
Mycobacterium chelonae infection (bacterial infection)
Pseudomonal sepsis (pseudomonas infections are diseases caused by a bacterium from the genus pseudomonas)
Secondary immunodeficiency (lack of immunity due to some disease)
Viral infection
Death
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Bacterial infection

10-19:

Arthralgia (joint pain)
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Back pain
Congestive cardiomyopathy (weakening of heart muscle)
Diastolic dysfunction
Dyspnoea exertional (breathlessness or shortness of breath)
Osteonecrosis (death of bone)
Osteoporosis (bones weak and more likely to break)
Systolic dysfunction (impaired ventricular contraction)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

20-29:

n/a

30-39:

n/a

40-49:

Bacterial infection
Cellulitis (infection under the skin)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Fungal infection
Lymphopenia (an abnormally low level of lymphocytes in the blood)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 13 people, 52.00%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 5 people, 20.00%
Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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