Diamox and Alphagan p drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diamox (acetazolamide) and Alphagan p (brimonidine tartrate). Common drug interactions include mucosal ulceration among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Diamox and Alphagan p. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.

What is Diamox?

Diamox has active ingredients of acetazolamide. It is often used in pseudotumor cerebri. eHealthMe is studying from 4,711 Diamox users. Check the latest studies of Diamox.

What is Alphagan p?

Alphagan p has active ingredients of brimonidine tartrate. It is often used in glaucoma. eHealthMe is studying from 6,579 Alphagan p users. Check the latest studies of Alphagan p.



On Aug, 04, 2026

68 people who take Diamox and Alphagan p together, and have interactions are studied.

Diamox and Alphagan p drug interactions.

What are the common drug interactions of Diamox and Alphagan P, by gender? *:

female:

  1. Mucosal ulceration (ulcers of mucous membrane)
  2. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
  3. Myalgia (muscle pain)
  4. Nephrogenic anaemia (anaemia due to kidney disease)
  5. Onychoclasis (breaking of the nails)
  6. Onychomycosis (fungal infection of the nail)
  7. Oral disorder (mouth disease)
  8. Osteonecrosis of jaw (death of bone of jaw)
  9. Peripheral vascular disorder
  10. Photopsia (presence of perceived flashes of light)

male:

  1. Drug ineffective
  2. Intraocular pressure increased
  3. Bladder disorder
  4. Blepharochalasis (inflammation of the eyelid that is characterized by exacerbations and remissions of eyelid oedema)
  5. Blindness
  6. Burning sensation
  7. Calculus urinary (stone in urinary system)
  8. Cataract (clouding of the lens inside the eye)
  9. Conjunctivitis (pink eye)
  10. Corneal degeneration (abnormal deposition of substances in the transparent front part of the eye)

What are the common drug interactions of Diamox and Alphagan P, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Perichondritis (inflammation of the perichondrium, a layer of connective tissue which surrounds cartilage)
  3. Pericoronitis (inflammation of the gingiva surrounding the crown of a tooth)
  4. Subcutaneous abscess
  5. Swelling face
  6. Bone loss
  7. Ear neoplasm (tour in ear)
  8. Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage))
  9. Eye swelling
  10. Neoplasm of orbit (a tumour of cavity of eye that holds the globe)

10-19:

n/a

20-29:

  1. Suture related complication
  2. Eye irritation
  3. Intraocular pressure increased
  4. Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
  5. Vitritis (inflammation of the vitreous humour of the eye)

30-39:

n/a

40-49:

  1. Calculus urinary (stone in urinary system)
  2. Haematuria (presence of blood in urine)
  3. Urine transitional cells present

50-59:

  1. Blood iron decreased
  2. Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
  3. Cardiac failure congestive
  4. Carotid bruit (sound heard over the carotid artery area during auscultation)
  5. Chest pain
  6. Cholecystitis (infection of gallbladder)
  7. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  8. Constipation
  9. Contusion (a type of hematoma of tissue in which capillaries)
  10. Decreased interest

60+:

  1. Corneal opacity (scarring or clouding of the cornea)
  2. Asthenia (weakness)
  3. Diarrhoea
  4. Dysphonia (speech disorder attributable to a disorder of phonation)
  5. Electrolyte depletion (act of decreasing electrolyte markedly)
  6. Eye infection viral
  7. Flat anterior chamber of eye
  8. Glossodynia (a burning or painful sensation in the tongue)
  9. Impaired healing
  10. Laryngitis (inflammation of the larynx)

What are the existing conditions these people have? *

  1. Intraocular Pressure Increased: 7 people, 10.29%
  2. Diabetes: 6 people, 8.82%
  3. High Blood Pressure: 5 people, 7.35%
  4. Angle Closure Glaucoma (term used for several ocular diseases that ultimately result in increased intraocular pressure (iop) and decreased visual acuity): 4 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Diamox and Alphagan p?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Diamox and Alphagan p:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Diamox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Alphagan p:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Diamox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Alphagan p and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on acetazolamide and brimonidine tartrate (the active ingredients of Diamox and Alphagan p, respectively), and Diamox and Alphagan p (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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