Diastat and Fentanyl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diastat (diazepam) and Fentanyl (fentanyl citrate). Common drug interactions include blood pressure increased among females and drug abuse among males.

The phase IV clinical study analyzes what interactions people have when they take Diastat and Fentanyl. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Diastat?

Diastat has active ingredients of diazepam. eHealthMe is studying from 2,104 Diastat users. Check the latest studies of Diastat.

What is Fentanyl?

Fentanyl has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 73,301 Fentanyl users. Check the latest studies of Fentanyl.

On Jul, 21, 2026

11 people who take Diastat and Fentanyl together, and have interactions are studied.

What are the common drug interactions of Diastat and Fentanyl, by gender? *:

female:

Blood pressure increased
Abnormal behaviour
Acute hepatic failure
Completed suicide (act of taking one's own life)
Cyclic vomiting syndrome (prolonged episodes of severe nausea, vomiting)
Defaecation urgency (a sudden compelling urge to defecate)
Drug effect decreased
Drug ineffective
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Heart rate increased

male:

Drug abuse
Drug toxicity
Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart)
Poisoning
Accident
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cardiomegaly (increased size of heart than normal)
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Pancreatitis acute (sudden inflammation of pancreas)
Pulmonary congestion (congestion in the lungs)

What are the common drug interactions of Diastat and Fentanyl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Drug abuse
Drug toxicity
Poisoning
Accident
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cardiomegaly (increased size of heart than normal)
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Pulmonary congestion (congestion in the lungs)
Pulmonary oedema (fluid accumulation in the lungs)
Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart)

40-49:

Completed suicide (act of taking one's own life)

50-59:

Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
International normalised ratio increased
Palpitations (feelings or sensations that your heart is pounding or racing)
Somnolence (a state of near-sleep, a strong desire for sleep)
Acute hepatic failure
Blood pressure increased
Defaecation urgency (a sudden compelling urge to defecate)
Drug effect decreased
Drug ineffective
Grand mal convulsion (a type of generalized seizure that affects the entire brain)

60+:

Pancreatitis acute (sudden inflammation of pancreas)
Poisoning

What are the existing conditions these people have? *

Post Herpetic Neuralgia (neuralgia caused by the varicella zoster virus): 1 person, 9.09%
Impaired Gastric Emptying: 1 person, 9.09%
Gastrointestinal Motility Disorder (abnormal intestinal contractions): 1 person, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 9.09%
Dyskinesia (abnormality or impairment of voluntary movement): 1 person, 9.09%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 9.09%
Chondrocalcinosis (crystal deposition disease): 1 person, 9.09%
Cholangitis (infection of the bile duct): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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