Diastat and Reglan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diastat (diazepam) and Reglan (metoclopramide hydrochloride). Common drug interactions include convulsion among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Diastat and Reglan. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Diastat?

Diastat has active ingredients of diazepam. eHealthMe is studying from 2,104 Diastat users. Check the latest studies of Diastat.

What is Reglan?

Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.

On Jul, 15, 2026

13 people who take Diastat and Reglan together, and have interactions are studied.

What are the common drug interactions of Diastat and Reglan, by gender? *:

female:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Muscular weakness (muscle weakness)
Pneumonia
Febrile neutropenia (fever with reduced white blood cells)
Blood glucose increased
Cardiac arrest
Dehydration (dryness resulting from the removal of water)
Hypovolaemia (a decreased volume of circulating blood in the body)
Lethargy (tiredness)
Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)

male:

Dyspnoea (difficult or laboured respiration)
Oxygen saturation decreased
Pneumonia
Impaired gastric emptying
Mobility decreased (ability to move is reduced)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Upper respiratory tract infection
Weight increased

What are the common drug interactions of Diastat and Reglan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Muscular weakness (muscle weakness)
Mobility decreased (ability to move is reduced)
Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
Respiratory failure (inadequate gas exchange by the respiratory system)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Stress
Upper respiratory tract infection
Urinary retention (the inability to completely or partially empty the bladder)

10-19:

Colitis ulcerative (inflammation of colon with ulcer)
Febrile neutropenia (fever with reduced white blood cells)
Dyspnoea (difficult or laboured respiration)
Oxygen saturation decreased
Pneumonia
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 61.54%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 38.46%
Agitation (state of anxiety or nervous excitement): 5 people, 38.46%
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 5 people, 38.46%
Renal Tubular Acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys): 5 people, 38.46%
Pain: 5 people, 38.46%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 5 people, 38.46%
Cerebral Palsy: 5 people, 38.46%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 5 people, 38.46%
Fever: 5 people, 38.46%

* Approximation only. Some reports may have incomplete information.

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