Diclegis and Ondansetron drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diclegis (doxylamine succinate; pyridoxine hydrochloride) and Ondansetron (ondansetron). Common drug interactions include gestational diabetes among females.

The phase IV clinical study analyzes what interactions people have when they take Diclegis and Ondansetron. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Diclegis?

Diclegis has active ingredients of doxylamine succinate; pyridoxine hydrochloride. eHealthMe is studying from 404 Diclegis users. Check the latest studies of Diclegis.

What is Ondansetron?

Ondansetron has active ingredients of ondansetron. It is often used in nausea. eHealthMe is studying from 122,738 Ondansetron users. Check the latest studies of Ondansetron.

On Jul, 17, 2026

11 people who take Diclegis and Ondansetron together, and have interactions are studied.

Diclegis and Ondansetron drug interactions.

What are the common drug interactions of Diclegis and Ondansetron, by gender? *:

female:

Gestational diabetes (diabetes in pregnancy)
Influenza
Fatigue (feeling of tiredness)
Impaired driving ability
Maternal exposure during pregnancy (use of substance during pregnancy)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Pain
Pruritus (severe itching of the skin)
Maternal exposure before pregnancy (use of substance before pregnancy)
Pneumonia

male:

n/a

What are the common drug interactions of Diclegis and Ondansetron, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Gestational diabetes (diabetes in pregnancy)
Influenza
Fatigue (feeling of tiredness)
Impaired driving ability
Pain
Pruritus (severe itching of the skin)
Maternal exposure before pregnancy (use of substance before pregnancy)
Pneumonia
Pre-eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman)
Sinusitis (inflammation of sinus)

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 18.18%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 18.18%
Humoral Immune Defect (impairment of humoral immunity): 2 people, 18.18%
Drowsiness: 2 people, 18.18%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 18.18%
Birth Control: 2 people, 18.18%
Premature Delivery: 1 person, 9.09%
Morning Sickness (sickness in morning during pregnancy): 1 person, 9.09%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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