Diclofenac and Serevent drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Diclofenac (diclofenac) and Serevent (salmeterol xinafoate). Common drug interactions include chronic kidney disease among females and gastrointestinal infection among males.
The phase IV clinical study analyzes what interactions people have when they take Diclofenac and Serevent. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Diclofenac?
Diclofenac has active ingredients of diclofenac. eHealthMe is studying from 41,319 Diclofenac users. Check the latest studies of Diclofenac.
What is Serevent?
Serevent has active ingredients of salmeterol xinafoate. It is often used in asthma. eHealthMe is studying from 15,586 Serevent users. Check the latest studies of Serevent.
14 people who take Diclofenac and Serevent together, and have interactions are studied.

What are the common drug interactions of Diclofenac and Serevent, by gender? *:
female:
- Chronic kidney disease
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Euphoric mood (excessively happy but may become angry or irritable)
- Influenza
- Pneumonia
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
- Pruritus (severe itching of the skin)
- Spinal fusion surgery
male:
- Gastrointestinal infection (infection of stomach and intestine)
- Aspartate aminotransferase increased
- C-reactive protein increased
- Dysstasia (difficulty in standing)
- Fatigue (feeling of tiredness)
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Glomerular filtration rate increased
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Leukocytosis (increased white blood cells)
- Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
What are the common drug interactions of Diclofenac and Serevent, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Blood magnesium decreased
- Blood urea decreased
- C-reactive protein increased
- Chronic kidney disease
- Dysstasia (difficulty in standing)
- Fatigue (feeling of tiredness)
- Glomerular filtration rate increased
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Leukocytosis (increased white blood cells)
60+:
- Influenza
- Pneumonia
- Spinal fusion surgery
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 21.43%
- Immunodeficiency Common Variable: 3 people, 21.43%
- Stress And Anxiety: 2 people, 14.29%
- Infection: 2 people, 14.29%
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2 people, 14.29%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 14.29%
- Depression: 2 people, 14.29%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 14.29%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 14.29%
- Blood Pressure Abnormal: 2 people, 14.29%
* Approximation only. Some reports may have incomplete information.
Do you take Diclofenac and Serevent?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Diclofenac (41,319 reports)
- Serevent (15,586 reports)
Browse all drug interactions of Diclofenac and Serevent:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Diclofenac:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Serevent:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Diclofenac and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Serevent and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on diclofenac and salmeterol xinafoate (the active ingredients of Diclofenac and Serevent, respectively), and Diclofenac and Serevent (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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