Didronel and Arthrotec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Didronel (etidronate disodium) and Arthrotec (diclofenac sodium; misoprostol). Common drug interactions include muscular weakness among females and myocardial ischaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Didronel and Arthrotec. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Didronel?

Didronel has active ingredients of etidronate disodium. eHealthMe is studying from 1,587 Didronel users. Check the latest studies of Didronel.

What is Arthrotec?

Arthrotec has active ingredients of diclofenac sodium; misoprostol. It is often used in arthritis. eHealthMe is studying from 11,986 Arthrotec users. Check the latest studies of Arthrotec.

On Jul, 17, 2026

22 people who take Didronel and Arthrotec together, and have interactions are studied.

Didronel and Arthrotec drug interactions.

What are the common drug interactions of Didronel and Arthrotec, by gender? *:

female:

Muscular weakness (muscle weakness)
Oedema peripheral (superficial swelling)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Fracture delayed union (delayed cure of broken bone)
Scar
Anxiety
Aortic valve incompetence
Cardiac failure congestive
Confusion

male:

Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart)

What are the common drug interactions of Didronel and Arthrotec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal discomfort
Anxiety
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Depression
Emotional distress
Fall
Femur fracture
Low turnover osteopathy (slow removal of old bone and its replacement by new bone)
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)

40-49:

n/a

50-59:

n/a

60+:

Abdominal discomfort
Fall
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Fracture delayed union (delayed cure of broken bone)
Scar
Aortic valve incompetence
Cardiac failure congestive
Confusion
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 10 people, 45.45%
Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 3 people, 13.64%
Osteoporosis (bones weak and more likely to break): 3 people, 13.64%
Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 13.64%

* Approximation only. Some reports may have incomplete information.

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