Digoxin and Apriso drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Digoxin (digoxin) and Apriso (mesalamine). Common drug interactions include diverticulitis among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Digoxin and Apriso. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.

What is Apriso?

Apriso has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 3,439 Apriso users. Check the latest studies of Apriso.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

20 people who take Digoxin and Apriso together, and have interactions are studied.

What are the common drug interactions of Digoxin and Apriso, by gender? *:

female:

Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Frequent bowel movements
Inflammation
Intestinal obstruction
Intestinal stenosis (partial obstruction that causes the centre opening of the intestine to become narrower)
Lethargy (tiredness)
Pulmonary thrombosis (scarring in the lungs)
Nasopharyngitis (inflammation of the nasopharynx)
Pneumonia
Thrombosis (formation of a blood clot inside a blood vessel)

male:

Drug ineffective
Eye swelling
Herpes zoster
Injection site haemorrhage (bleeding from injection site)
Skin cancer

What are the common drug interactions of Digoxin and Apriso, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Drug ineffective

60+:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pulmonary thrombosis (scarring in the lungs)
Abscess intestinal (collections of pus-intestinal)
Blood iron decreased
Haematochezia (passage of stools containing blood)
Hypotension (abnormally low blood pressure)
Intestinal ulcer
Leukocytosis (increased white blood cells)
Normochromic normocytic anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits)
Oedema mucosal (swelling of mucous membrane)

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 30.00%
Psoriasis (immune-mediated disease that affects the skin): 4 people, 20.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 15.00%
Glaucoma (increased fluid pressure in the eye with vision loss): 3 people, 15.00%
Thyroid Diseases: 2 people, 10.00%
Heart Rate Increased: 2 people, 10.00%
Pain: 2 people, 10.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 5.00%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 1 person, 5.00%
Hyperkeratosis (thickening of the outer layer of the skin): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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