Digoxin and Depo-medrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Digoxin (digoxin) and Depo-medrol (methylprednisolone acetate). Common drug interactions include cardiac failure congestive among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Digoxin and Depo-medrol. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.

What is Depo-medrol?

Depo-medrol has active ingredients of methylprednisolone acetate. It is often used in birth control. eHealthMe is studying from 5,933 Depo-medrol users. Check the latest studies of Depo-medrol.

On Aug, 07, 2026

44 people who take Digoxin and Depo-medrol together, and have interactions are studied.

Digoxin and Depo-medrol drug interactions.

What are the common drug interactions of Digoxin and Depo-Medrol, by gender? *:

female:

Cardiac failure congestive
Asthenia (weakness)
Palpitations (feelings or sensations that your heart is pounding or racing)
Back pain
Myalgia (muscle pain)
Urinary tract infection
Oedema peripheral (superficial swelling)
Mitral valve incompetence (inefficient heart valve)
Calculus ureteric (stone in ureter)
Fatigue (feeling of tiredness)

male:

Cardiac failure congestive
Dyspnoea (difficult or laboured respiration)
Injury
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Oedema peripheral (superficial swelling)
Mitral valve incompetence (inefficient heart valve)
Multiple injuries
Palpitations (feelings or sensations that your heart is pounding or racing)
Pneumonia
Pulse absent

What are the common drug interactions of Digoxin and Depo-Medrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain upper
Anaemia (lack of blood)
Anxiety
Asthenia (weakness)
Atrioventricular dissociation (av block)
Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
Back pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cardiomegaly (increased size of heart than normal)

30-39:

n/a

40-49:

n/a

50-59:

Injury
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Blood uric acid increased
Calculus ureteric (stone in ureter)
Hydronephrosis (water inside the kidney)
Meniscus lesion (lesion of a crescent-shaped piece of cartilage between the femur and the tibia)
Chest pain
Gastritis (inflammation of stomach)
Multiple injuries
Angina pectoris (chest pain due to ischemia of the heart muscle)

60+:

Nausea (feeling of having an urge to vomit)
Mitral valve incompetence (inefficient heart valve)
Myalgia (muscle pain)
Palpitations (feelings or sensations that your heart is pounding or racing)
Cough
Diarrhoea
Fatigue (feeling of tiredness)
Oedema peripheral (superficial swelling)
Pain
Pain in extremity

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 13.64%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 6.82%
Cardiac Failure Congestive: 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

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