Digoxin and Elmiron drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Digoxin (digoxin) and Elmiron (pentosan polysulfate sodium). Common drug interactions include drug ineffective among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Digoxin and Elmiron. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.

What is Elmiron?

Elmiron has active ingredients of pentosan polysulfate sodium. It is often used in interstitial cystitis (ic). eHealthMe is studying from 10,215 Elmiron users. Check the latest studies of Elmiron.

On Aug, 01, 2026

17 people who take Digoxin and Elmiron together, and have interactions are studied.

What are the common drug interactions of Digoxin and Elmiron, by gender? *:

female:

Drug ineffective
Nephrogenic anaemia (anaemia due to kidney disease)
Pain
Constipation
Contusion (a type of hematoma of tissue in which capillaries)
Diarrhoea
Fungal infection
Gastrointestinal tract irritation
Anaemia (lack of blood)
Arthritis (form of joint disorder that involves inflammation of one or more joints)

male:

Anaemia (lack of blood)
Chest pain
Colonoscopy
Dyspnoea (difficult or laboured respiration)
Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
Pneumonia
Thrombosis (formation of a blood clot inside a blood vessel)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))

What are the common drug interactions of Digoxin and Elmiron, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Red blood cell count decreased
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Thyroid cyst
Thyroid mass
Vasoconstriction (constriction of blood vessels, which increases blood pressure)
Volume blood decreased

30-39:

n/a

40-49:

n/a

50-59:

Chronic kidney disease
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nephrogenic anaemia (anaemia due to kidney disease)
Obstructive airways disorder (a progressive disease that makes it hard to breathe)
Renal failure (kidney dysfunction)
Somnolence (a state of near-sleep, a strong desire for sleep)

60+:

Malaise (a feeling of general discomfort or uneasiness)
Anaemia (lack of blood)
Blood magnesium decreased
Blood potassium decreased
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Colonoscopy
Cough
Dizziness
Drug ineffective
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 23.53%
Cystitis Interstitial (unknown cause characterized by bladder pain): 4 people, 23.53%
High Blood Cholesterol: 4 people, 23.53%
Cardiac Disorder: 3 people, 17.65%
Bladder Disorder: 2 people, 11.76%
Depression: 2 people, 11.76%
Urinary Tract Infection: 1 person, 5.88%
Dry Eyes (lack of adequate tears): 1 person, 5.88%
Genitourinary Tract Neoplasm (genitourinary tract cancer): 1 person, 5.88%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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