Digoxin and Geodon drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Digoxin (digoxin) and Geodon (ziprasidone hydrochloride). Common drug interactions include pain among females and delusion among males.
The phase IV clinical study analyzes what interactions people have when they take Digoxin and Geodon. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.
What is Digoxin?
Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.
What is Geodon?
Geodon has active ingredients of ziprasidone hydrochloride. It is often used in bipolar disorder. eHealthMe is studying from 19,504 Geodon users. Check the latest studies of Geodon.
43 people who take Digoxin and Geodon together, and have interactions are studied.

What are the common drug interactions of Digoxin and Geodon, by gender? *:
female:
- Pain
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Multiple injuries
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Dysarthria (speech disorder)
- International normalised ratio increased
male:
- Delusion (a false belief or opinion)
- Confusional state
- Abnormal behaviour
- Aggression
- Blood potassium decreased
- Coma (state of unconsciousness lasting more than six hours)
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Dyskinesia (abnormality or impairment of voluntary movement)
- Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
- Hypotension (abnormally low blood pressure)
What are the common drug interactions of Digoxin and Geodon, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Arthropathy
- Benign neoplasm (benign (non-cancerous) tumour)
- Calcium deficiency (lack of calcium)
- Dyspnoea (difficult or laboured respiration)
- Dysuria (painful or difficult urination)
- Hand fracture
- Impaired work ability
- Infusion site cellulitis
- Infusion site induration
40-49:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Abdominal pain upper
- Anaemia (lack of blood)
- Anger
- Anxiety
- Asthma
- Brain neoplasm (tumour of brain)
- Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
50-59:
- Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
- Suicidal ideation
- Suicide attempt
- Type 2 diabetes mellitus
- Acute myocardial infarction (acute heart attack)
- Acute respiratory failure
- Anaemia of chronic disease
- Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
- Back pain
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
60+:
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Cardiac failure congestive
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Dysarthria (speech disorder)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- International normalised ratio increased
What are the existing conditions these people have? *
- Agitation (state of anxiety or nervous excitement): 9 people, 20.93%
- Heart Rate Irregular: 7 people, 16.28%
- Depression: 6 people, 13.95%
- Stress And Anxiety: 3 people, 6.98%
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 6.98%
- Psychotic Disorder: 3 people, 6.98%
* Approximation only. Some reports may have incomplete information.
Do you take Digoxin and Geodon?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Digoxin and Geodon:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Digoxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Geodon:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Digoxin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Geodon and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on digoxin and ziprasidone hydrochloride (the active ingredients of Digoxin and Geodon, respectively), and Digoxin and Geodon (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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