Digoxin and Northera drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Digoxin (digoxin) and Northera (droxidopa). Common drug interactions include extrasystoles among females and loss of consciousness among males.

The phase IV clinical study analyzes what interactions people have when they take Digoxin and Northera. It is created by eHealthMe based on reports of 63 people who take the same drugs from the FDA, and is updated regularly.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.

What is Northera?

Northera has active ingredients of droxidopa. eHealthMe is studying from 22,874 Northera users. Check the latest studies of Northera.

On Jul, 16, 2026

63 people who take Digoxin and Northera together, and have interactions are studied.

What are the common drug interactions of Digoxin and Northera, by gender? *:

female:

Extrasystoles
Head injury
Hypertension (high blood pressure)
Migraine (headache)
Syncope (loss of consciousness with an inability to maintain postural tone)
Upper limb fracture
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cyst (a closed sac)
Death
Hallucination (an experience involving the perception of something not present)

male:

Loss of consciousness
Decreased appetite
Hypertension (high blood pressure)
Confusional state
Peripheral swelling
Pneumonia
Urinary tract infection
Hypotension (abnormally low blood pressure)
Syncope (loss of consciousness with an inability to maintain postural tone)
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the common drug interactions of Digoxin and Northera, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Decreased appetite
Weight decreased

30-39:

n/a

40-49:

Blood pressure increased
Death
Headache (pain in head)
Migraine (headache)

50-59:

Drug ineffective
Anxiety
Blood pressure increased
Heart rate increased
Loss of consciousness
Palpitations (feelings or sensations that your heart is pounding or racing)
Panic attack
Presyncope
Tinnitus (a ringing in the ears)
Activities of daily living impaired

60+:

Loss of consciousness
Decreased appetite
Dyspnoea (difficult or laboured respiration)
Palpitations (feelings or sensations that your heart is pounding or racing)
Confusional state
Hypertension (high blood pressure)
Pneumonia
Urinary tract infection
Peripheral swelling
Hypotension (abnormally low blood pressure)

What are the existing conditions these people have? *

Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 26 people, 41.27%
Parkinson's Disease: 19 people, 30.16%
High Blood Pressure: 9 people, 14.29%
Autonomic Neuropathy (malfunction of the autonomic nervous system (ans)): 8 people, 12.70%
Dizziness: 5 people, 7.94%
Hypotension (abnormally low blood pressure): 4 people, 6.35%

* Approximation only. Some reports may have incomplete information.

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