Dilantin and Eprex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dilantin (phenytoin sodium) and Eprex (epoetin alfa). Common drug interactions include aplasia pure red cell among females and red cell aplasia among males.

The phase IV clinical study analyzes what interactions people have when they take Dilantin and Eprex. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Dilantin?

Dilantin has active ingredients of phenytoin sodium. It is often used in epilepsy. eHealthMe is studying from 20,858 Dilantin users. Check the latest studies of Dilantin.

What is Eprex?

Eprex has active ingredients of epoetin alfa. eHealthMe is studying from 5,554 Eprex users. Check the latest studies of Eprex.

On Jul, 27, 2026

13 people who take Dilantin and Eprex together, and have interactions are studied.

What are the common drug interactions of Dilantin and Eprex, by gender? *:

female:

Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Reticulocyte count decreased
Serum ferritin increased
Small intestinal haemorrhage (bleeding from small intestine)
Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
H1n1 influenza (flu (influenza), which is caused by virus influenza a (h1n1))
Influenza
Multi-organ failure (multisystem organ failure)

male:

Red cell aplasia (a type of anaemia affecting the precursors to red blood cells)
Reticulocyte count decreased
Haemoglobin increased
Intracardiac thrombus (presence of a circumscribed mass with heart wall)
Therapeutic response decreased (less preventive response)
Thrombosis (formation of a blood clot inside a blood vessel)
Drug effect decreased
Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
Atrial thrombosis (blood clot that develops in an artery)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)

What are the common drug interactions of Dilantin and Eprex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
Faecal occult blood positive
Haemoglobin increased
Reticulocyte count decreased
Therapeutic response decreased (less preventive response)

50-59:

n/a

60+:

Reticulocyte count decreased
Red cell aplasia (a type of anaemia affecting the precursors to red blood cells)
H1n1 influenza (flu (influenza), which is caused by virus influenza a (h1n1))
Haemoglobin abnormal
Influenza
Intracardiac thrombus (presence of a circumscribed mass with heart wall)
Multi-organ failure (multisystem organ failure)
Thrombosis (formation of a blood clot inside a blood vessel)
Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

What are the existing conditions these people have? *

Prostate Cancer: 2 people, 15.38%
Multiple Myeloma (cancer of the plasma cells): 2 people, 15.38%
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 2 people, 15.38%
High Blood Pressure: 2 people, 15.38%
Nephrogenic Anaemia (anaemia due to kidney disease): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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