Dilantin and Omniscan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dilantin (phenytoin sodium) and Omniscan (gadodiamide). Common drug interactions include oedema among females and nephrogenic systemic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Dilantin and Omniscan. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Dilantin?

Dilantin has active ingredients of phenytoin sodium. It is often used in epilepsy. eHealthMe is studying from 20,858 Dilantin users. Check the latest studies of Dilantin.

What is Omniscan?

Omniscan has active ingredients of gadodiamide. eHealthMe is studying from 6,169 Omniscan users. Check the latest studies of Omniscan.

On Jul, 04, 2026

51 people who take Dilantin and Omniscan together, and have interactions are studied.

Dilantin and Omniscan drug interactions.

What are the common drug interactions of Dilantin and Omniscan, by gender? *:

female:

Oedema (fluid collection in tissue)
Bone pain
Stress
Finger deformity (a deformed position of the finger)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Emotional distress
Pain of skin
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
Abasia (inability to walk)
Abdominal pain

male:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Pain
Heart rate decreased
Heart rate increased
Heart rate irregular
Injury
Lower respiratory tract infection
Nasopharyngitis (inflammation of the nasopharynx)
Skin fibrosis (fibrous tissue formation on skin)
Wheezing (a high-pitched whistling sound made while you breath)

What are the common drug interactions of Dilantin and Omniscan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain
Asthenia (weakness)
Cellulitis (infection under the skin)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Dyspnoea (difficult or laboured respiration)
Klebsiella sepsis (klebsiella causes a potentially fatal whole-body inflammation)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Pneumonia
Pulmonary alveolar haemorrhage (acute bleeding)
Pyrexia (fever)

30-39:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Joint range of motion decreased (disease of joint movement)
Oedema peripheral (superficial swelling)
Pain
Joint contracture (a permanent shortening of a muscle or joint)
Skin hypertrophy (skin cells enlarges)
Skin tightness
Anxiety
Skin induration (an abnormally hard spot or area on the skin)
Pain in extremity

40-49:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Oedema peripheral (superficial swelling)
Mobility decreased (ability to move is reduced)
Pain
Skin induration (an abnormally hard spot or area on the skin)
Joint range of motion decreased (disease of joint movement)
Skin fibrosis (fibrous tissue formation on skin)
Skin hypertrophy (skin cells enlarges)
Skin tightness
General physical health deterioration (weak health status)

50-59:

Rash papular (redness with papule)
Skin atrophy (wasting of skin)
Skin ulcer
Peau d'orange (orange peel skin)
Renal impairment (severely reduced kidney function)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Pain
Skin induration (an abnormally hard spot or area on the skin)
Skin hypertrophy (skin cells enlarges)
Skin tightness

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Pain
Pain of skin
Peau d'orange (orange peel skin)
Pruritus (severe itching of the skin)
Scar
Skin hypertrophy (skin cells enlarges)
Skin lesion
Skin tightness

What are the existing conditions these people have? *

Nuclear Magnetic Resonance Imaging Brain: 36 people, 70.59%
Pain: 16 people, 31.37%
Nuclear Magnetic Resonance Imaging Abdominal: 8 people, 15.69%
Haemorrhage Intracranial (bleeding within the skull): 8 people, 15.69%
Weakness: 6 people, 11.76%
Headache (pain in head): 6 people, 11.76%
Stress And Anxiety: 5 people, 9.80%
Back Pain: 5 people, 9.80%
High Blood Pressure: 5 people, 9.80%
Multiple Myeloma (cancer of the plasma cells): 5 people, 9.80%

* Approximation only. Some reports may have incomplete information.

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