Dilantin and Rhinocort drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dilantin (phenytoin sodium) and Rhinocort (budesonide). Common drug interactions include bronchitis chronic among females and agranulocytosis among males.

The phase IV clinical study analyzes what interactions people have when they take Dilantin and Rhinocort. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Dilantin?

Dilantin has active ingredients of phenytoin sodium. It is often used in epilepsy. eHealthMe is studying from 20,859 Dilantin users. Check the latest studies of Dilantin.

What is Rhinocort?

Rhinocort has active ingredients of budesonide. It is often used in allergies. eHealthMe is studying from 7,139 Rhinocort users. Check the latest studies of Rhinocort.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

24 people who take Dilantin and Rhinocort together, and have interactions are studied.

Dilantin and Rhinocort drug interactions.

What are the common drug interactions of Dilantin and Rhinocort, by gender? *:

female:

Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Burning sensation
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Colitis (inflammation of colon)
Contusion (a type of hematoma of tissue in which capillaries)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Decreased appetite
Diarrhoea
Discomfort

male:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Asthenia (weakness)
Atherosclerosis (disorder of the arteries)
Blood pressure increased
Bone disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Calculus urinary (stone in urinary system)
Colitis ulcerative (inflammation of colon with ulcer)

What are the common drug interactions of Dilantin and Rhinocort, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)

10-19:

Calculus urinary (stone in urinary system)
Crystalluria present
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Oliguria (not enough urine)
Renal colic (renal pain)
Ureteric obstruction
Urinary retention (the inability to completely or partially empty the bladder)

20-29:

Activities of daily living impaired
Hypertension (high blood pressure)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthma
Back pain
Blood sodium decreased
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Confusional state
Cough

30-39:

Anxiety
Blood cholesterol increased
Confusional state
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Decreased appetite
Depression
Discomfort
Drug abuser
Drug dependence

40-49:

Rhinorrhoea (watery mucus discharge from the nose)
Screaming (a long loud piercing cry)
Stress incontinence (leak urine with things like coughing, sneezing or exercise)
Suicide attempt
Thermal burn (burn by heat)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Anxiety
Cellulitis (infection under the skin)
Depression
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)

50-59:

Colitis ulcerative (inflammation of colon with ulcer)
Fall

60+:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Atherosclerosis (disorder of the arteries)
Blood pressure increased
Bone disorder
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Drug dependence
Ejection fraction decreased (systolic heart failure)
Impaired healing

What are the existing conditions these people have? *

Pain: 6 people, 25.00%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 16.67%
High Blood Cholesterol: 3 people, 12.50%
Hypersensitivity: 2 people, 8.33%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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